Polyomavirus microRNAs circulating in biological fluids during viral persistence
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DOI: 10.1002/rmv.1927
Abstract: Increasing evidence suggests that microRNA‐mediated gene silencing, detected during exosome intercellular communication between cells, may be exploited by persistent human viruses. Recently, it has been reported that human polyomaviruses encode microRNAs that downregulate large T… read more here.
Keywords: polyomavirus micrornas; viral persistence; micrornas circulating; jcpyv bkpyv ... See more keywords
Footprints of BK and JC polyomaviruses in specimens from females affected by spontaneous abortion
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DOI: 10.1093/humrep/dey375
Abstract: STUDY QUESTION Are JC polyomavirus (JCPyV) and BK polyomavirus (BKPyV) infections associated with spontaneous abortion (SA)? SUMMARY ANSWER There is no association of JCPyV or BKPyV with SA. WHAT IS KNOWN ALREADY A large number… read more here.
Keywords: spontaneous abortion; dna; 104 cells; jcpyv bkpyv ... See more keywords
The Oxindole GW-5074 Inhibits JC Polyomavirus Infection and Spread by Antagonizing the MAPK-ERK Signaling Pathway
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DOI: 10.1128/mbio.03583-22
Abstract: Human polyomaviruses, such as JCPyV and BKPyV, cause significant morbidity and mortality in immunocompromised or immunomodulated patients. There are no treatments for polyomavirus-induced diseases other than restoration of immune function. We discovered that the oxindole… read more here.
Keywords: oxindole 5074; jcpyv bkpyv; infection; polyomavirus induced ... See more keywords
The differential presence of human polyomaviruses, JCPyV and BKPyV, in prostate cancer and benign prostate hypertrophy tissues
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DOI: 10.1186/s12885-021-08862-w
Abstract: Background Studies have shown that human polyomavirus infection may be associated with various human cancers. We investigated the potential relationship between the prevalence of JCPyVor BKPyV and prostate cancer (PC) in patients from Taiwan. Methods… read more here.
Keywords: cancer; jcpyv bkpyv; infection; prostate cancer ... See more keywords
Detection Analysis and Study of Genomic Region Variability of JCPyV, BKPyV, MCPyV, HPyV6, HPyV7 and QPyV in the Urine and Plasma of HIV-1-Infected Patients
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DOI: 10.3390/v14112544
Abstract: Since it was clearly established that HIV/AIDS predisposes to the infection, persistence or reactivation of latent viruses, the prevalence of human polyomaviruses (HPyVs) among HIV-1-infected patients and a possible correlation between HPyVs and HIV sero-status… read more here.
Keywords: jcpyv bkpyv; mcpyv; bkpyv mcpyv; hpyv6 hpyv7 ... See more keywords