The DNA damage response promotes polyomavirus JC infection by nucleus to cytoplasm NF- kappaB activation
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DOI: 10.1186/s12985-017-0707-7
Abstract: BackgroundInfection of glial cells by human neurotropic polyomavirus JC (JCV), the causative agent of the CNS demyelinating disease progressive multifocal leukoencephalopathy (PML), rapidly inflicts damage to cellular DNA. This activates DNA damage response (DDR) signaling… read more here.
Keywords: dna; infection; jcv infection; jcv ... See more keywords