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   Articles with "jeg" as a keyword



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Long noncoding RNA H19 promotes chemotherapy resistance in choriocarcinoma cells

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recommendations! Published in 2019 at "Journal of Cellular Biochemistry"

DOI: 10.1002/jcb.28775

Abstract: Choriocarcinoma (CC) is a trophoblast tumor prone to early distant organ metastases. At present, the main treatment for CC is chemotherapy, but chemotherapy resistance readily occurs and leads to treatment failure. H19 is a long… read more here.

Keywords: jeg mtx; resistance; jeg cells; jeg ... See more keywords
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MicroRNA-126 suppresses the invasion of trophoblast-model JEG-3 cells by targeting LIN28A.

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recommendations! Published in 2021 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2021.01.077

Abstract: Inadequate trophoblast invasion and impaired trophoblast-induced vascular remodeling are features of preeclampsia. In this context, an angiogenesis-related microRNA, miR-126, is abnormally expressed in preeclampsia placentas, but its role in trophoblast development remains unclear. The purpose… read more here.

Keywords: 126 suppresses; mir 126; invasion; jeg ... See more keywords
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Application of a JEG-3 organoid model to study HLA-G function in the trophoblast

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recommendations! Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2023.1130308

Abstract: The human placenta is a unique temporary organ with a mysterious immune tolerance. The formation of trophoblast organoids has advanced the study of placental development. HLA-G is uniquely expressed in the extravillous trophoblast (EVT) and… read more here.

Keywords: function; hla; jeg; trophoblast ... See more keywords
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Forskolin Induces Endocrine Disturbance in Human JEG-3 Placental Cells

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recommendations! Published in 2022 at "Toxics"

DOI: 10.3390/toxics10070355

Abstract: Forskolin, used in folk medicine since ancient times, is now available as a dietary supplement, with an indication as a fat burner and appetite suppressant. However, the safety of forskolin is poorly documented especially for… read more here.

Keywords: forskolin; jeg; pregnant women; placental cells ... See more keywords
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Selenocystine inhibits JEG-3 cell growth in vitro and in vivo by triggering oxidative damage-mediated S-phase arrest and apoptosis

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recommendations! Published in 2018 at "Journal of Cancer Research and Therapeutics"

DOI: 10.4103/jcrt.jcrt_864_17

Abstract: Background: Selenocystine (SeC) is a nutritionally available selenoamino acid presenting novel anticancer potential against human cancers. However, neither the effects nor mechanism of SeC against choriocarcinoma growth has been clarified yet. This study investigated the… read more here.

Keywords: growth; apoptosis; oxidative damage; jeg ... See more keywords