Lidocine potentiates the cytotoxicity of 5‐fluorouracil to choriocarcinoma cells by downregulating ABC transport proteins expression
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DOI: 10.1002/jcb.28913
Abstract: Choriocarcinoma is a gestational trophoblastic cancer, which often occurs in the first 3 months of pregnancy. 5‐Fluorouracil (5‐Fu) is the widely used chemotherapeutic drug for choriocarcinoma but limited by drug resistance. Lidocaine, an aminamide‐type anesthetic,… read more here.
Keywords: jeg jar; choriocarcinoma; cells downregulating; cytotoxicity ... See more keywords
Secreted Frizzled Related Protein 2 Modulates Epithelial–Mesenchymal Transition and Stemness via Wnt/β-Catenin Signaling in Choriocarcinoma
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DOI: 10.1159/000494862
Abstract: Background/Aims: Choriocarcinoma (CC) is a highly aggressive gestational trophoblastic neoplasia; however, the underlying molecular mechanisms of its invasiveness and metastasis remain poorly understood. Human secreted frizzled-related protein 2 (SFRP2) could function as a tumor promoter… read more here.
Keywords: stemness; jeg jar; wnt; sfrp2 ... See more keywords