Jerveratrum-Type Steroidal Alkaloids Inhibit β-1,6-Glucan Biosynthesis in Fungal Cell Walls
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DOI: 10.1128/spectrum.00873-21
Abstract: Non-Candida albicans Candida species (NCAC) are on the rise as a cause of mycosis. Many antifungal drugs are less effective against NCAC, limiting the available therapeutic agents. ABSTRACT The limited number of available effective agents… read more here.
Keywords: jerveratrum type; jervine; glucan biosynthesis; type steroidal ... See more keywords
A New UPLC-MS/MS Method Validated for Quantification of Jervine in Rat Plasma and the Study of Its Pharmacokinetics in Rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Analytical Methods in Chemistry"
DOI: 10.1155/2019/5163625
Abstract: The aim of this study was to develop an ultraperformance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) method to assess the concentration of jervine in rat plasma and its pharmacokinetics. Diazepam was used as internal standard (IS).… read more here.
Keywords: rat plasma; uplc method; jervine; study ... See more keywords