Jib Vibration and Payload Swing of Tower Cranes in the Case of Trolley Motion
Sign Up to like & getrecommendations! Published in 2021 at "Arabian Journal for Science and Engineering"
DOI: 10.1007/s13369-021-05804-3
Abstract: Based on the assumptions that the tower and counter jib of the tower cranes are rigid bodies in the case of trolley motion, the jib of the tower cranes is taken as a cantilever beam.… read more here.
Keywords: payload; trolley motion; jib; tower cranes ... See more keywords
JIB-04, A Small Molecule Histone Demethylase Inhibitor, Selectively Targets Colorectal Cancer Stem Cells by Inhibiting the Wnt/β-Catenin Signaling Pathway
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-24903-0
Abstract: Although several epigenetic modulating drugs are suggested to target cancer stem cells (CSCs), additional identification of anti-CSC drugs is still necessary. Here we showed that JIB-04, a pan-selective inhibitor of histone demethylase(s), was identified as… read more here.
Keywords: stem cells; cancer stem; colorectal cancer; cancer ... See more keywords
Control of Beam-Pendulum Dynamics in a Tower Crane With a Slender Jib Transporting a Distributed-Mass Load
Sign Up to like & getrecommendations! Published in 2023 at "IEEE Transactions on Industrial Electronics"
DOI: 10.1109/tie.2022.3148741
Abstract: Tower cranes with slender jib transporting bulky loads are commonly applied in the construction site. Human-operated commands induce vibrations of the cantilever jib, swing, and twisting of the suspended load. Coupled oscillations among jib deflection,… read more here.
Keywords: deflection load; jib transporting; jib deflection; slender jib ... See more keywords
JIB-04 Has Broad-Spectrum Antiviral Activity and Inhibits SARS-CoV-2 Replication and Coronavirus Pathogenesis
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DOI: 10.1128/mbio.03377-21
Abstract: The coronavirus disease 2019 (COVID-19), the disease caused by SARS-CoV-2 infection, is an ongoing public health disaster worldwide. Although several vaccines are available as a preventive measure and the FDA approval of an orally bioavailable… read more here.
Keywords: sars cov; infection; activity; replication ... See more keywords
Small molecules targeting histone demethylase genes (KDMs) inhibit growth of temozolomide-resistant glioblastoma cells
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DOI: 10.18632/oncotarget.16820
Abstract: In glioblastoma several histone demethylase genes (KDM) are overexpressed compared to normal brain tissue and the development of Temozolomide (TMZ) resistance is accompanied by the transient further increased expression of KDM5A and other KDMs following… read more here.
Keywords: glioblastoma cells; jib; histone demethylase; demethylase genes ... See more keywords
The Jumonji-domain histone demethylase inhibitor JIB-04 deregulates oncogenic programs and increases DNA damage in Ewing Sarcoma, resulting in impaired cell proliferation and survival, and reduced tumor growth
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.26011
Abstract: Ewing Sarcoma is an aggressive malignant neoplasm affecting children and young adults. Ewing Sarcoma is driven by transcription factor fusion oncoproteins, most commonly EWS/Fli1. While some patients can be cured with high-dose, multi-agent, chemotherapy, those… read more here.
Keywords: sarcoma; cell; jib; ewing sarcoma ... See more keywords
Sensitization of Resistant Breast Cancer Cells with a Jumonji Family Histone Demethylase Inhibitor
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DOI: 10.3390/cancers14112631
Abstract: Simple Summary Using a cell culture model of resistant breast cancer cells with the phenotype that is often responsible for the early relapse of triple-negative breast cancer, namely, the persistence of these cells in reversible… read more here.
Keywords: cancer; cell; breast cancer; jib ... See more keywords
JIB-04, a Pan-Inhibitor of Histone Demethylases, Targets Histone-Lysine-Demethylase-Dependent AKT Pathway, Leading to Cell Cycle Arrest and Inhibition of Cancer Stem-Like Cell Properties in Hepatocellular Carcinoma Cells
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23147657
Abstract: JIB-04, a pan-histone lysine demethylase (KDM) inhibitor, targets drug-resistant cells, along with colorectal cancer stem cells (CSCs), which are crucial for cancer recurrence and metastasis. Despite the advances in CSC biology, the effect of JIB-04… read more here.
Keywords: cell; inhibition; histone lysine; jib ... See more keywords