Pneumocystis jirovecii pneumonia in children. A retrospective study in a single center over three decades.
Sign Up to like & getrecommendations! Published in 2019 at "Enfermedades infecciosas y microbiologia clinica"
DOI: 10.1016/j.eimc.2019.05.005
Abstract: INTRODUCTION Pneumocystis jirovecii pneumonia (PJP) is a life-threatening condition in immunocompromised children. Our aim is to analyze the epidemiologic and clinical characteristics of PJP cases in our setting, describing the prognosis and related risk factors.… read more here.
Keywords: jirovecii pneumonia; pneumocystis jirovecii; retrospective study; jirovecii ... See more keywords
Évaluation du kit de PCR en temps réel MycoGENIE® Pneumocystis jirovecii pour le diagnostic moléculaire de la pneumocystose
Sign Up to like & getrecommendations! Published in 2017 at "Journal De Mycologie Medicale"
DOI: 10.1016/j.mycmed.2017.04.056
Abstract: Pneumocystis jirovecii (Pj) est un champignon pathogene opportuniste strictement humain. Il colonise transitoirement et sans symptome l’arbre respiratoire des patients immunocompetents, et peut etre responsable d’infections pulmonaires severes chez les patients immunodeprimes. Le diagnostic biologique… read more here.
Keywords: kit mycogenie; pneumocystis jirovecii; kit; ont ete ... See more keywords
Pneumocytis jirovecii et PCR quantitative : pneumonie ou colonisation à Pneumocystis jirovecii ?
Sign Up to like & getrecommendations! Published in 2020 at "Revue Des Maladies Respiratoires"
DOI: 10.1016/j.rmr.2019.12.006
Abstract: Resume Contexte La pertinence de la PCR quantitative pour faire le diagnostic de pneumonie a Pneumocystis jirovecii (PPJ) est debattue en cas de charge fongique faible. Methodes Etude retrospective monocentrique des patients ayant subi un… read more here.
Keywords: pneumocystis; pcr quantitative; pcr; colonisation ... See more keywords
Pneumocystis jirovecii pneumonia in systemic autoimmune rheumatic disease: A case-control study.
Sign Up to like & getrecommendations! Published in 2017 at "Seminars in arthritis and rheumatism"
DOI: 10.1016/j.semarthrit.2016.09.009
Abstract: INTRODUCTION AND OBJECTIVES Pneumocystis jirovecii pneumonia (PJP) is an opportunistic fungal infection that affects the immunocompromised. Patients with systemic autoimmune rheumatic disease are increasingly recognised as an at-risk clinical population with a high mortality. This… read more here.
Keywords: pjp; rheumatic disease; disease; systemic autoimmune ... See more keywords
Development of a fully automated PCR assay for the detection of Pneumocystis jirovecii using the GENECUBE system.
Sign Up to like & getrecommendations! Published in 2018 at "Medical mycology"
DOI: 10.1093/mmy/myy145
Abstract: We developed a fully automated polymerase chain reaction (PCR) assay for the detection of Pneumocystis jirovecii using the GENECUBE system. This assay was evaluated against an in-house real-time PCR assay using 82 bronchoalveolar lavage and… read more here.
Keywords: detection; genecube system; fully automated; pcr assay ... See more keywords
Metagenomic next-generation sequencing for the diagnosis of Pneumocystis jirovecii pneumonia in solid organ transplant recipients
Sign Up to like & getrecommendations! Published in 2022 at "Chinese Medical Journal"
DOI: 10.1097/cm9.0000000000002120
Abstract: To the Editor: Pneumocystis jirovecii (P. jirovecii) pneumonia (PJP) is an opportunistic infection that usually occurs in immunosuppressed patients. Solid organ transplant (SOT) recipients have a high incidence of PJP due to the use of… read more here.
Keywords: pneumocystis jirovecii; metagenomic next; jirovecii; organ transplant ... See more keywords
Apparent Absence of Selective Pressure on Pneumocystis jirovecii Organisms in Patients with Prior Methotrexate Exposure
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DOI: 10.1128/aac.00990-22
Abstract: Pneumocystis jirovecii infections occur in patients treated with methotrexate (MTX) because of immunosuppressive effects of this highly potent dihydrofolate reductase (DHFR) inhibitor. Conversely, MTX may act as an anti-P. jirovecii drug and consequently may exert… read more here.
Keywords: jirovecii; jirovecii organisms; pneumocystis jirovecii; selective pressure ... See more keywords
The Fascinating Echinocandin-Treated Mouse Model of Pneumocystis murina To Understand Pneumocystis jirovecii
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DOI: 10.1128/aac.00992-18
Abstract: Pneumocystis jirovecii is a transmissible fungus that causes life-threatening pneumonia in immunosuppressed patients. Pneumocystis pneumonia (PCP) remains the most frequent AIDS-defining illness in developed countries, while it is also observed with an increasing frequency in… read more here.
Keywords: pneumocystis; fascinating echinocandin; pneumocystis jirovecii; treated mouse ... See more keywords
Mechanisms of Surface Antigenic Variation in the Human Pathogenic Fungus Pneumocystis jirovecii
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DOI: 10.1128/mbio.01470-17
Abstract: ABSTRACT Microbial pathogens commonly escape the human immune system by varying surface proteins. We investigated the mechanisms used for that purpose by Pneumocystis jirovecii. This uncultivable fungus is an obligate pulmonary pathogen that in immunocompromised… read more here.
Keywords: antigenic variation; surface; family; gene ... See more keywords
Positive Pneumocystis jirovecii Sputum PCR Results with Negative Bronchoscopic PCR Results in Suspected Pneumocystis Pneumonia
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DOI: 10.1155/2018/6283935
Abstract: Introduction The diagnostic standard for Pneumocystis jirovecii pneumonia (PCP) is direct microscopic identification; however, in recent years, polymerase chain reaction (PCR) from bronchoalveolar lavage (BAL) samples to detect Pneumocystis nucleic acids has proven to be… read more here.
Keywords: pcr results; sputum; pneumocystis; pcr ... See more keywords
Serum-based diagnosis of Pneumocystis pneumonia by detection of Pneumocystis jirovecii DNA and 1,3-β-D-glucan in HIV-infected patients: a retrospective case control study
Sign Up to like & getrecommendations! Published in 2019 at "BMC Infectious Diseases"
DOI: 10.1186/s12879-019-4289-4
Abstract: BackgroundPneumocystis jirovecii pneumonia (PCP) is one of the most common HIV-related opportunistic infections. The diagnosis of PCP is based on analyses from respiratory tract specimens which may require the invasive procedure of a diagnostic bronchoscopy.… read more here.
Keywords: pneumocystis; pneumocystis jirovecii; serum; infected patients ... See more keywords