Articles with "jmjd1c" as a keyword



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JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis

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Published in 2019 at "Leukemia"

DOI: 10.1038/s41375-018-0354-z

Abstract: Abnormal metabolism is a fundamental hallmark of cancer and represents a therapeutic opportunity, yet its regulation by oncogenes remains poorly understood. Here, we uncover that JMJD1C, a jumonji C (JmjC)-containing H3K9 demethylase, is a critical… read more here.

Keywords: dysregulation contributes; metabolic dysregulation; mediated metabolic; jmjd1c ... See more keywords
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Circular RNA circ_0006168 enhances Taxol resistance in esophageal squamous cell carcinoma by regulating miR-194-5p/JMJD1C axis

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Published in 2021 at "Cancer Cell International"

DOI: 10.1186/s12935-021-01984-y

Abstract: Background Chemoresistance is one of the major obstacles for cancer therapy in the clinic. Circular RNAs (circRNAs) are involved in the pathogenesis of esophageal squamous cell carcinoma (ESCC) and chemoresistance. This study aimed to explore… read more here.

Keywords: circ 0006168; taxol resistance; jmjd1c; cell ... See more keywords