Articles with "jmjd1c mediated" as a keyword



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JMJD1C-mediated metabolic dysregulation contributes to HOXA9-dependent leukemogenesis

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Published in 2019 at "Leukemia"

DOI: 10.1038/s41375-018-0354-z

Abstract: Abnormal metabolism is a fundamental hallmark of cancer and represents a therapeutic opportunity, yet its regulation by oncogenes remains poorly understood. Here, we uncover that JMJD1C, a jumonji C (JmjC)-containing H3K9 demethylase, is a critical… read more here.

Keywords: dysregulation contributes; metabolic dysregulation; mediated metabolic; jmjd1c ... See more keywords