Interplay among H3K9-editing enzymes SUV39H1, JMJD2C and SRC-1 drives p66Shc transcription and vascular oxidative stress in obesity
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DOI: 10.1093/eurheartj/ehx615
Abstract: Aims Accumulation of reactive oxygen species (ROS) promotes vascular disease in obesity, but the underlying molecular mechanisms remain poorly understood. The adaptor p66Shc is emerging as a key molecule responsible for ROS generation and vascular… read more here.
Keywords: obesity; jmjd2c src; p66shc; suv39h1 jmjd2c ... See more keywords