LAUSR

JMJD3 facilitates C/EBPβ-centered transcriptional program to exert oncorepressor activity in AML

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0 Published in 2018 at "Nature Communications"

DOI: 10.1038/s41467-018-05548-z

Abstract: JMJD3, a stress-inducible H3K27 demethylase, plays a critical regulatory role in the initiation and progression of malignant hematopoiesis. However, how this histone modifier affects in a cell type-dependent manner remains unclear. Here, we show that… read more here.

Keywords: jmjd3; oncorepressor; jmjd3 facilitates; ebp centered ... See more keywords