Targeting histone demethylases JMJD3 and UTX: selenium as a potential therapeutic agent for cervical cancer
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DOI: 10.1186/s13148-024-01665-3
Abstract: The intriguing connection between selenium and cancer resembles a captivating puzzle that keeps researchers engaged and curious. While selenium has shown promise in reducing cancer risks through supplementation, its interaction with epigenetics in cervical cancer… read more here.
Keywords: histone demethylases; cancer; selenium; cervical cancer ... See more keywords
Inhibitor of H3K27 demethylase JMJD3/UTX GSK-J4 is a potential therapeutic option for castration resistant prostate cancer
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DOI: 10.18632/oncotarget.19100
Abstract: Androgen receptor (AR) mediates initiation and progression of prostate cancer (PCa); AR-driven transcription is activated by binding of androgens to the ligand-binding domain (LBD) of AR. Androgen ablation therapy offers only a temporary relief of… read more here.
Keywords: jmjd3; jmjd3 utx; prostate cancer; castration resistant ... See more keywords