Aberrant JmjC domain-containing protein 8 (JMJD8) expression promotes activation of AKT and tumor epithelial–mesenchymal transition
Sign Up to like & getrecommendations! Published in 2020 at "Oncogene"
DOI: 10.1038/s41388-020-01446-1
Abstract: Posttranslational modifications of histone and nonhistone proteins greatly influence numerous molecular events in multiple diseases. Jumonji domain-containing proteins are a family functioning as histone demethylase. Jumonji domain-containing protein 8 (JMJD8) is Jumonji C (JmjC) domain-only… read more here.
Keywords: domain containing; jmjd8; domain; containing protein ... See more keywords
JMJD8 Functions as a Novel AKT1 Lysine Demethylase
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24010460
Abstract: JMJD8 is a protein from the JMJD family that only has the JmjC domain. Studies on the function of JMJD8 indicate that JMJD8 is involved in signaling pathways, including AKT/NF-ÎşB, and thus affects cell proliferation… read more here.
Keywords: demethylase; jmjd8; novel akt1; lysine demethylase ... See more keywords