Evaluation of JNJ-54717793 a Novel Brain Penetrant Selective Orexin 1 Receptor Antagonist in Two Rat Models of Panic Attack Provocation
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DOI: 10.3389/fphar.2017.00357
Abstract: Orexin neurons originating in the perifornical and lateral hypothalamic area are highly reactive to anxiogenic stimuli and have strong projections to anxiety and panic-associated circuitry. Recent studies support a role for the orexin system and… read more here.
Keywords: jnj; jnj 54717793; brain; orexin receptor ... See more keywords