Pan-serotype dengue virus inhibitor JNJ-A07 targets NS4A-2K-NS4B interaction with NS2B/NS3 and blocks replication organelle formation
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DOI: 10.1038/s41467-024-50437-3
Abstract: Dengue fever represents a significant medical and socio-economic burden in (sub)tropical regions, yet antivirals for treatment or prophylaxis are lacking. JNJ-A07 was described as highly active against the different genotypes within each serotype of the… read more here.
Keywords: jnj a07; ns4a ns4b; jnj; dengue virus ... See more keywords