Herpud1 deficiency could reduce amyloid-β40 expression and thereby suppress homocysteine-induced atherosclerosis by blocking the JNK/AP1 pathway
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Physiology and Biochemistry"
DOI: 10.1007/s13105-020-00741-5
Abstract: Homocysteine (Hcy) is considered an independent risk factor for various cardiovascular diseases including atherosclerosis which is associated with lipid metabolism, inflammation, and oxidative stress. Results from our previous study suggested that Hcy-induced atherosclerosis could be… read more here.
Keywords: hcy; induced atherosclerosis; jnk ap1; expression ... See more keywords
EST12 regulates Myc expression and enhances anti-mycobacterial inflammatory response via RACK1-JNK-AP1-Myc immune pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.943174
Abstract: c-Myc (Myc) is a well-known transcription factor that regulates many essential cellular processes. Myc has been implicated in regulating anti-mycobacterial responses. However, its precise mechanism in modulating mycobacterial immunity remains elusive. Here, we found that… read more here.
Keywords: anti mycobacterial; expression; myc; jnk ap1 ... See more keywords