Pro-BDNF Contributes to Hypoxia/Reoxygenation Injury in Myocardial Microvascular Endothelial Cells: Roles of Receptors p75NTR and Sortilin and Activation of JNK and Caspase 3
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/3091424
Abstract: The aim of this study was to identify the role of the precursor of the brain-derived neurotrophic factor (pro-BDNF) in myocardial hypoxia/reoxygenation injury (H/R) and to address the underlying mechanisms. For this purpose, myocardial microvascular… read more here.
Keywords: pro bdnf; p75ntr sortilin; jnk caspase; injury ... See more keywords
Microglia-derived ADAM9 promote GHRH neurons pyroptosis by Mad2L2-JNK-caspase-1 pathway in subarachnoid hemorrhage
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Neuroinflammation"
DOI: 10.1186/s12974-024-03299-x
Abstract: The incidence of growth hormone deficiency (GHD) after subarachnoid hemorrhage (SAH) is significantly higher than that of other neuroendocrine disorders, but the mechanism is still elusive. We used mass spectrometry to identify differentially expressed proteins… read more here.
Keywords: ghd; subarachnoid hemorrhage; jnk caspase; mad2l2 jnk ... See more keywords
Tomatidine Attenuates C48/80-induced Inflammatory Responses in HMC-1 Cells and is Associated with Modulation of the JNK/AP-1/NF-κB/Caspase-1 Pathway.
Sign Up to like & getrecommendations! Published in 2025 at "Current topics in medicinal chemistry"
DOI: 10.2174/0115680266392868250527045507
Abstract: BACKGROUND Existing research has suggested that the JNK/AP-1/NF-κB/Caspase-1 pathway may account for the activation of HMC-1 mast cells under inflammatory circumstances, and our current study aims to validate whether Tomatidine could act as the candidate… read more here.
Keywords: c48; jnk caspase; hmc cells; caspase ... See more keywords