Unraveling the Design and Discovery of c-Jun N-Terminal Kinase Inhibitors and Their Therapeutic Potential in Human Diseases.
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DOI: 10.1021/acs.jmedchem.1c01947
Abstract: c-Jun N-terminal kinases (JNKs), members of the mitogen-activated protein kinase (MAPK) family, are encoded by three genes: jnk1, jnk2, and jnk3. JNKs are involved in the pathogenesis and development of many diseases, such as neurodegenerative… read more here.
Keywords: design discovery; kinase; jun terminal; unraveling design ... See more keywords