Enterococcus faecium HDRsEf1 inhibits LPS-induced downregulation of ZO-1 expression via TLR2/4-mediated JNK/AP-1 signalling pathways.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of applied microbiology"
DOI: 10.1111/jam.15167
Abstract: AIMS ZO-1 is a key regulatory tight junction protein that plays an important role in maintaining gastrointestinal health. In this study, we investigated the protective effect and regulation mechanism of the probiotic Enterococcus faecium HDRsEf1… read more here.
Keywords: enterococcus faecium; lps induced; expression; jnk signalling ... See more keywords
Notoginsenoside R1 attenuates oxidative stress-induced osteoblast dysfunction through JNK signalling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular and molecular medicine"
DOI: 10.1111/jcmm.17054
Abstract: Oxidative stress (OS)-induced mitochondrial damage and the subsequent osteoblast dysfunction contributes to the initiation and progression of osteoporosis. Notoginsenoside R1 (NGR1), isolated from Panax notoginseng, has potent antioxidant effects and has been widely used in… read more here.
Keywords: medicine; stress induced; signalling pathway; jnk signalling ... See more keywords
Response to: Correspondence on ‘Mechanical overloading promotes chondrocyte senescence and osteoarthritis development through downregulating FBXW7’ by Loeser et al
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2022-222710
Abstract: In January 2022, we reported an important role for FBXW7 in the association between mechanical overloading, chondrocyte senescence and cartilage ageing in the pathology of osteoarthritis (OA). Our data support the idea that JNK signalling… read more here.
Keywords: mechanical overloading; chondrocyte senescence; jnk; correspondence ... See more keywords
Two-Faced: Roles of JNK Signalling During Tumourigenesis in the Drosophila Model
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.00042
Abstract: The highly conserved c-Jun N-terminal Kinase (JNK) signalling pathway has many functions, regulating a diversity of processes: from cell movement during embryogenesis to the stress response of cells after environmental insults. Studies modelling cancer using… read more here.
Keywords: two faced; faced roles; jnk; roles jnk ... See more keywords