Platycodin D (PD) attenuates myocardial apoptosis mediated by JNK-SIRT1-HSF1-IGF-IIR-Caspase-3 signaling in hypertensive conditions
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DOI: 10.1016/j.jff.2017.04.008
Abstract: Abstract Hypertension is a progressive condition. The compensatory left ventricular hypertrophy maintains cardiac output. It leads to myocardial remodeling characterized by fibrosis, insufficient vascularization, even apoptosis and heart failure. This condition involves a possible mechanism… read more here.
Keywords: apoptosis; sirt1 hsf1; jnk sirt1; igf iir ... See more keywords