A Jocic-type approach for a practical and scalable synthesis of pyrrolonaphthoxazepine (PNOX)-based potent proapoptotic agents
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DOI: 10.1016/j.tetlet.2018.11.005
Abstract: Abstract We developed a Jocic-type protocol for the construction of the pyrrolonaphthoxazepine (PNOX) core. After an initial investigation based on the isolation of a trichloromethyl carbinol derivative, we shifted our attention towards a multicomponent single-step… read more here.
Keywords: pyrrolonaphthoxazepine pnox; type approach; jocic type; pnox based ... See more keywords