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Published in 2019 at "Brain and Behavior"
DOI: 10.1002/brb3.1332
Abstract: Determination of antibodies against the John Cunningham virus (JCV) is an important tool for risk stratification in Natalizumab‐treated multiple sclerosis (MS) patients. Six‐monthly testing has been suggested for anti‐JCV antibody negative patients and patients with…
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Keywords:
john cunningham;
antibody;
prospective study;
cunningham virus ... See more keywords
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Published in 2022 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004093
Abstract: ABSTRACT A 69-year-old woman presented with progressive dysarthria and cognitive deficits. On MRI, a T2-hyperintense, non-contrast-enhancing lesion was found in the left precentral area. 18F-FET and 18F-FDG PET scans revealed faint amino acid uptake and…
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Keywords:
progressive multifocal;
acid uptake;
john cunningham;
amino acid ... See more keywords
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Published in 2020 at "European Neurology"
DOI: 10.1159/000510849
Abstract: Introduction: Presence of anti-JC-virus antibodies (JCVAbs) is associated with the increased risk of natalizumab (NAT)-related progressive multifocal leukoencephalopathy (PML). Little is known about seroconversion rate and time to seroconversion in relapsing-remitting multiple sclerosis (RRMS) patients…
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Keywords:
john cunningham;
cunningham virus;
seroconversion;
seroconversion rate ... See more keywords
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Published in 2021 at "Current neuropharmacology"
DOI: 10.2174/1570159x19666211111123202
Abstract: BACKGROUND Progressive Multifocal Leukoencephalopathy (PML) is an opportunistic infection caused by John Cunningham virus (JCV) reactivation, potentially associated to natalizumab (NTZ) treatment for Multiple Sclerosis (MS). The anti-JCV antibodies titre (JCV index) increases during NTZ…
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Keywords:
jcv index;
disease modifying;
cunningham virus;
john cunningham ... See more keywords