Articles with "john wort" as a keyword



Preventing Neurons and Glial Cells Destruction in Substantia Nigra Pars Compacta and Striatum Using St. John's Wort and Stem Cells on Parkinson's Model.

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Published in 2025 at "Brain and behavior"

DOI: 10.1002/brb3.71124

Abstract: St. John's wort (Hypericum perforatum) has been used for centuries as a medicinal plant to remedy external disorders such as burns and wounds, as well as internal disorders such as nerve pain, anxiety, and depression.… read more here.

Keywords: cells parkinson; stem; stem cells; john wort ... See more keywords

Effect of St. John’s wort oil and olive oil on the postoperative complications after third molar surgery: randomized, double-blind clinical trial

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Published in 2020 at "Clinical Oral Investigations"

DOI: 10.1007/s00784-020-03639-0

Abstract: Objectives This multicenter study aimed to evaluate the effects of St. John’s wort oil and virgin olive oil on the postoperative complications and compare this with chlorhexidine gluconate plus benzydamine hydrochloride mouthwash after the removal… read more here.

Keywords: john wort; wort oil; third molar; postoperative complications ... See more keywords

STABILITY OF SOME BIOLOGICALLY ACTIVE SUBSTANCES IN EXTRACTS AND PREPARATIONS BASED ON ST. JOHN’S WORT (HYPERICUM PERFORATUM L.) AND SAGE (SALVIA OFFICINALIS L.)

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Published in 2020 at "Industrial Crops and Products"

DOI: 10.1016/j.indcrop.2020.112879

Abstract: Abstract Quality, authenticity and stability control of medicinal plant materials and preparations based on them is an important challenge in industries using substances and materials derived from plants. St. John’s wort (Hypericum perforatum L.) and… read more here.

Keywords: perforatum; preparations based; stability; john wort ... See more keywords

Effect of St.John's wort (Hypericum perforatum) oily extract for the care and treatment of pressure sores; a case report.

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Published in 2017 at "Journal of ethnopharmacology"

DOI: 10.1016/j.jep.2016.12.030

Abstract: ETHNOPHARMACOLOGICAL RELEVANCE Topical formulations such as oily extracts or ointments prepared with the flowering aerial parts of St. John's wort (Hypericum perforatum L., Hypericaceae) have been used in the management of a wide range dermatological… read more here.

Keywords: wort; john wort; treatment pressure; oily extract ... See more keywords

Spectrophotometric Fluoride Determination Using St. John’s Wort Extract as a Green Chromogenic Complexant for Al(III)

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Published in 2022 at "ACS Omega"

DOI: 10.1021/acsomega.2c06048

Abstract: In this study, we applied an innovative approach of green analytical chemistry to develop a novel and eco-friendly chromogenic agent for fluoride determination by making use of the nontoxic Al(III)-flavonoid complex in a natural extract… read more here.

Keywords: fluoride determination; extract; john wort;

St. John's wort extract Ze 117 alters the membrane fluidity of C6 glioma cells by influencing cellular cholesterol metabolism

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Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-60562-0

Abstract: Chronic stress is associated with major depressive disorder (MDD). Increased glucocorticoid levels caused by uncontrolled release through the hypothalamic‒pituitary‒adrenal (HPA) axis can cause changes in the lipid content of the cellular plasma membrane. These changes… read more here.

Keywords: fluidity; effect; cellular cholesterol; metabolism ... See more keywords

Influence of St. John’s Wort on Intravenous Fentanyl Pharmacokinetics, Pharmacodynamics, and Clinical Effects

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Published in 2019 at "Anesthesiology"

DOI: 10.1097/aln.0000000000003065

Abstract: Background: Patients often use complementary and alternative herbal medicines, hence, potential exists for adverse herb–drug interactions. Fentanyl is metabolized by hepatic CYP3A4 and considered transported by blood–brain barrier P-glycoprotein. Both disposition processes could be upregulated… read more here.

Keywords: john wort; fentanyl pharmacokinetics; wort; pharmacokinetics pharmacodynamics ... See more keywords

A Randomized Split-Face Study of Photodynamic Therapy With St. John's Wort and Indole-3-Acetic Acid for the Treatment of Acne

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Published in 2023 at "Dermatologic Surgery"

DOI: 10.1097/dss.0000000000003742

Abstract: Supplemental Digital Content is Available in the Text. BACKGROUND St. John's wort (SJW) contains hypericin, a powerful photosensitizer with antimicrobial and anti-inflammatory activities. OBJECTIVE To compare the efficacy and safety of SJW-photodynamic therapy (PDT) with… read more here.

Keywords: indole acetic; treatment acne; acetic acid; john wort ... See more keywords

Utility of Therapeutic Drug Monitoring in Identifying Clinically Significant Interactions Between St. John's Wort and Prescription Drugs

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Published in 2023 at "Therapeutic Drug Monitoring"

DOI: 10.1097/ftd.0000000000001069

Abstract: Background: The general population widely uses herbal medicines, as they are regarded as effective and safe. St. John's wort, which is an effective herbal antidepressant, exhibits both pharmacokinetic and pharmacodynamic interactions with several drugs. The… read more here.

Keywords: interactions john; clinically significant; john wort; significant interactions ... See more keywords

St. John’s Wort accelerates the liver clearance of technetium-99-sestamibi in rats

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Published in 2018 at "Nuclear Medicine Communications"

DOI: 10.1097/mnm.0000000000000880

Abstract: Background The intense liver uptake of technetium-99-sestamibi (99mTc-MIBI) and photon scattering from the liver cause problems in quantitative perfusion interpretation. Hence, 99mTc-MIBI is a substrate for P-glycoprotein pump; variations in P-glycoprotein levels may affect liver… read more here.

Keywords: john wort; liver clearance; accelerates liver; technetium sestamibi ... See more keywords

Dose‐dependent induction of CYP3A activity by St. John's wort alone and in combination with rifampin

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Published in 2024 at "Clinical and Translational Science"

DOI: 10.1111/cts.70007

Abstract: The dose dependence of the effect of enzyme inducers and the effect of the combined administration of two inducers that exert their effect via the same induction pathway (pregnane X receptor) have not been well… read more here.

Keywords: 1800 day; administration; john wort; rifampin ... See more keywords