Genetics and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: What Have We Learned?
Sign Up to like & getrecommendations! Published in 2017 at "JAMA ophthalmology"
DOI: 10.1001/jamaophthalmol.2017.0136
Abstract: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are part of a spectrum of severe cutaneous reactions affecting skin and mucous membranes.1 Affected patients usually develop a prodrome of fever and malaise, followed by the… read more here.
Keywords: sjs ten; genetics; johnson syndrome; sjs ... See more keywords
Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures
Sign Up to like & getrecommendations! Published in 2017 at "Advances in Therapy"
DOI: 10.1007/s12325-017-0530-y
Abstract: IntroductionStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic conditions occurring in the inpatient setting. There is a lack of consensus regarding appropriate management of SJS and TEN.PurposeThe scientific… read more here.
Keywords: sjs ten; johnson syndrome; epidermal necrolysis; care ... See more keywords
Stevens-Johnson syndrome with vulvar involvement: A case report and literature review
Sign Up to like & getrecommendations! Published in 2022 at "Case Reports in Women's Health"
DOI: 10.1016/j.crwh.2022.e00404
Abstract: Stevens-Johnson syndrome is a rare, life-threatening mucocutaneous condition causing necrosis and detachment of the epidermis. Vulvovaginal involvement, seen in up to 70% of affected women, can lead to painful chronic conditions such as adenosis, hematocolpos,… read more here.
Keywords: involvement; case report; johnson syndrome; involvement case ... See more keywords
Society of Dermatology Hospitalists supportive care guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2020.02.066
Abstract: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions with high morbidity and mortality. Supportive care management of SJS/TEN is highly variable. A systematic review of the literature was performed by dermatologists, ophthalmologists,… read more here.
Keywords: dermatology; supportive care; johnson syndrome; management ... See more keywords
Acute pancreatic injuries: A complication of Stevens-Johnson syndrome/toxic epidermal necrolysis associated with cytotoxic immunocell activation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2020.06.043
Abstract: Abstract Background Complications involving internal organs are usually present in Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). However, pancreatic complications are rarely reported and studied. Objective To summarize clinical characteristics of SJS/TEN-associated acute pancreatic… read more here.
Keywords: sjs ten; pancreatic injuries; johnson syndrome; epidermal necrolysis ... See more keywords
Performance of ABCD-10 and SCORTEN Mortality Prediction Models in a Cohort of Patients with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2021.04.082
Abstract: BACKGROUND ABCD-10 has recently been proposed as an alternative to the SCORTEN model for predicting in-hospital mortality in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis. In contrast to SCORTEN, ABCD-10 incorporates prior dialysis and… read more here.
Keywords: abcd; johnson syndrome; mortality; syndrome toxic ... See more keywords
Inhibition of tumor necrosis factor improves conventional steroid therapy for Stevens-Johnson syndrome/toxic epidermal necrolysis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Academy of Dermatology"
DOI: 10.1016/j.jaad.2022.01.039
Abstract: BACKGROUND Systemic steroid therapies for Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) have been challenged due to their limited benefits. Whether additional tumor necrosis factor (TNF)-α inhibition provides an optimized approach remains unexplored. OBJECTIVE To investigate… read more here.
Keywords: epidermal necrolysis; johnson syndrome; inhibition; therapy ... See more keywords
Tenofovir-induced Stevens-Johnson syndrome in a patient with acute hepatitis B: A rare case report.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Pharmacists Association : JAPhA"
DOI: 10.1016/j.japh.2020.06.029
Abstract: OBJECTIVE To report a rare case of a hepatitis B patient who developed the Stevens-Johnson syndrome (SJS) secondary to tenofovir use. CASE SUMMARY A 61-year-old woman presented with complaints of jaundice, difficulty in swallowing, and… read more here.
Keywords: rare case; tenofovir; johnson syndrome; case ... See more keywords
Stevens-Johnson syndrome/toxic epidermal necrolysis successfully treated with Chinese herbal medicine Pi-Yan-Ning: A case report.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of integrative medicine"
DOI: 10.1016/j.joim.2021.10.001
Abstract: Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare adverse cutaneous reaction with a low incidence and high mortality. Despite posing a serious threat to patients' health and lives, there is no high-quality evidence for a… read more here.
Keywords: medicine; yan ning; johnson syndrome; case ... See more keywords
Corneal ectasia with Stevens–Johnson syndrome
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DOI: 10.1080/08164622.2021.1878835
Abstract: Corneal ectasia and Stevens–Johnson syndrome (SJS) are uncommon ocular conditions, both of which can be managed with scleral contact lenses to improve visual acuity, provide constant corneal lubrication, and decrease photophobia. Very few reports of… read more here.
Keywords: ectasia stevens; corneal; corneal ectasia; johnson syndrome ... See more keywords
Stevens-Johnson syndrome and toxic epidermal necrolysis: risk factors, causality assessment and potential prevention strategies
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2020.1740591
Abstract: ABSTRACT Introduction: The clinical manifestations of cutaneous adverse drug reactions are variable with different severity. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening severe cutaneous adverse reactions (SCARs) majorly caused by drugs and… read more here.
Keywords: epidermal necrolysis; johnson syndrome; risk factors; stevens johnson ... See more keywords