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   Articles with "johnson syndrome" as a keyword



Recovering From Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

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recommendations! Published in 2025 at "JAMA dermatology"

DOI: 10.1001/jamadermatol.2025.4345

Abstract: Importance Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) survivors experience substantial long-term sequelae. Research on physical symptoms experienced during acute hospitalization is well documented, but limited studies have been completed on the long-term biopsychosocial effects… read more here.

Keywords: sjs ten; long term; stevens johnson; johnson syndrome ... See more keywords

Genetics and Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: What Have We Learned?

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recommendations! Published in 2017 at "JAMA ophthalmology"

DOI: 10.1001/jamaophthalmol.2017.0136

Abstract: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are part of a spectrum of severe cutaneous reactions affecting skin and mucous membranes.1 Affected patients usually develop a prodrome of fever and malaise, followed by the… read more here.

Keywords: sjs ten; genetics; johnson syndrome; sjs ... See more keywords

Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures

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recommendations! Published in 2017 at "Advances in Therapy"

DOI: 10.1007/s12325-017-0530-y

Abstract: IntroductionStevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are two of the most severe dermatologic conditions occurring in the inpatient setting. There is a lack of consensus regarding appropriate management of SJS and TEN.PurposeThe scientific… read more here.

Keywords: sjs ten; johnson syndrome; epidermal necrolysis; care ... See more keywords

Stevens-Johnson syndrome with vulvar involvement: A case report and literature review

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recommendations! Published in 2022 at "Case Reports in Women's Health"

DOI: 10.1016/j.crwh.2022.e00404

Abstract: Stevens-Johnson syndrome is a rare, life-threatening mucocutaneous condition causing necrosis and detachment of the epidermis. Vulvovaginal involvement, seen in up to 70% of affected women, can lead to painful chronic conditions such as adenosis, hematocolpos,… read more here.

Keywords: involvement; case report; johnson syndrome; involvement case ... See more keywords
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Society of Dermatology Hospitalists supportive care guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults.

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recommendations! Published in 2020 at "Journal of the American Academy of Dermatology"

DOI: 10.1016/j.jaad.2020.02.066

Abstract: Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions with high morbidity and mortality. Supportive care management of SJS/TEN is highly variable. A systematic review of the literature was performed by dermatologists, ophthalmologists,… read more here.

Keywords: dermatology; supportive care; johnson syndrome; management ... See more keywords

Acute pancreatic injuries: A complication of Stevens-Johnson syndrome/toxic epidermal necrolysis associated with cytotoxic immunocell activation

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recommendations! Published in 2020 at "Journal of the American Academy of Dermatology"

DOI: 10.1016/j.jaad.2020.06.043

Abstract: Abstract Background Complications involving internal organs are usually present in Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). However, pancreatic complications are rarely reported and studied. Objective To summarize clinical characteristics of SJS/TEN-associated acute pancreatic… read more here.

Keywords: sjs ten; pancreatic injuries; johnson syndrome; epidermal necrolysis ... See more keywords
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Performance of ABCD-10 and SCORTEN Mortality Prediction Models in a Cohort of Patients with Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.

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recommendations! Published in 2021 at "Journal of the American Academy of Dermatology"

DOI: 10.1016/j.jaad.2021.04.082

Abstract: BACKGROUND ABCD-10 has recently been proposed as an alternative to the SCORTEN model for predicting in-hospital mortality in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis. In contrast to SCORTEN, ABCD-10 incorporates prior dialysis and… read more here.

Keywords: abcd; johnson syndrome; mortality; syndrome toxic ... See more keywords

Inhibition of tumor necrosis factor improves conventional steroid therapy for Stevens-Johnson syndrome/toxic epidermal necrolysis.

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recommendations! Published in 2022 at "Journal of the American Academy of Dermatology"

DOI: 10.1016/j.jaad.2022.01.039

Abstract: BACKGROUND Systemic steroid therapies for Stevens-Johnson syndrome (SJS)/toxic epidermal necrolysis (TEN) have been challenged due to their limited benefits. Whether additional tumor necrosis factor (TNF)-α inhibition provides an optimized approach remains unexplored. OBJECTIVE To investigate… read more here.

Keywords: epidermal necrolysis; johnson syndrome; inhibition; therapy ... See more keywords
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Tenofovir-induced Stevens-Johnson syndrome in a patient with acute hepatitis B: A rare case report.

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recommendations! Published in 2020 at "Journal of the American Pharmacists Association : JAPhA"

DOI: 10.1016/j.japh.2020.06.029

Abstract: OBJECTIVE To report a rare case of a hepatitis B patient who developed the Stevens-Johnson syndrome (SJS) secondary to tenofovir use. CASE SUMMARY A 61-year-old woman presented with complaints of jaundice, difficulty in swallowing, and… read more here.

Keywords: rare case; tenofovir; johnson syndrome; case ... See more keywords
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Stevens-Johnson syndrome/toxic epidermal necrolysis successfully treated with Chinese herbal medicine Pi-Yan-Ning: A case report.

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recommendations! Published in 2021 at "Journal of integrative medicine"

DOI: 10.1016/j.joim.2021.10.001

Abstract: Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) is a rare adverse cutaneous reaction with a low incidence and high mortality. Despite posing a serious threat to patients' health and lives, there is no high-quality evidence for a… read more here.

Keywords: medicine; yan ning; johnson syndrome; case ... See more keywords

Multiomic single-cell sequencing defines tissue-specific responses in Stevens-Johnson syndrome and toxic epidermal necrolysis

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recommendations! Published in 2024 at "Nature Communications"

DOI: 10.1038/s41467-024-52990-3

Abstract: Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is a rare but life-threatening cutaneous drug reaction mediated by human leukocyte antigen (HLA) class I-restricted CD8+ T cells. For unbiased assessment of cellular immunopathogenesis, here we perform… read more here.

Keywords: johnson syndrome; syndrome toxic; stevens johnson; cell ... See more keywords