Joint penalized spline modeling of multivariate longitudinal data, with application to HIV-1 RNA load levels and CD4 cell counts.
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DOI: 10.1111/biom.13339
Abstract: Motivated by the need to jointly model the longitudinal trajectories of HIV viral load levels and CD4 counts during the primary infection stage, we propose a joint penalized spline modeling approach that can be used… read more here.
Keywords: levels cd4; penalized spline; load levels; joint penalized ... See more keywords