Development of a joint population pharmacokinetic model of ezetimibe and its conjugated metabolite
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DOI: 10.1016/j.ejps.2018.11.018
Abstract: &NA; Ezetimibe (EZE) is an extensively used antihyperlipidemic drug with an important cholesterol lowering activity. It undergoes extensive first‐pass metabolism to form its active glucuronide metabolite (EZEG). Both drugs exhibit complex pharmacokinetic profiles attributed mainly… read more here.
Keywords: development joint; pharmacokinetic model; population pharmacokinetic; joint population ... See more keywords