The role of Dickkopf-1 in joint remodeling and fibrosis: A link connecting spondyloarthropathies and scleroderma?
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DOI: 10.1016/j.semarthrit.2016.08.014
Abstract: BACKGROUND Dickkopf-1 (Dkk-1) is a soluble inhibitor of the canonical Wnt pathway, which plays critical roles in embryonic development. Evidence suggests that this molecule regulates several aspects of both bone biology and fibrosis. OBJECTIVES To… read more here.
Keywords: fibrosis; remodeling fibrosis; role; joint remodeling ... See more keywords