Nuclear localization of a novel calpain-2 mediated junctophilin-2 C-terminal cleavage peptide promotes cardiomyocyte remodeling
Sign Up to like & getrecommendations! Published in 2020 at "Basic Research in Cardiology"
DOI: 10.1007/s00395-020-0807-1
Abstract: Heart failure (HF) is a leading cause of morbidity and mortality worldwide. Patients with HF exhibit a loss of junctophilin-2 (JPH2), a structural protein critical in forming junctional membrane complexes in which excitation–contraction takes place.… read more here.
Keywords: nuclear localization; cleavage; jph2 ctp; jph2 ... See more keywords