Self-Associating Poly(ethylene oxide)-block-poly(α-carboxyl-ε-caprolactone) Drug Conjugates for the Delivery of STAT3 Inhibitor JSI-124: Potential Application in Cancer Immunotherapy.
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DOI: 10.1021/acs.molpharmaceut.6b01119
Abstract: Constitutive activation of signal transducer and activator of transcription 3 (STAT3) in tumor cells and tumor associated dendritic cells (DCs) plays a major role in the progression of cancer. JSI-124 (cucurbitacin I) is a potent… read more here.
Keywords: jsi 124; poly; drug; cancer ... See more keywords
Effort-reward imbalance and job strain index associated with health-related quality of life for civil servants in a national survey: the mediation effect of job support and over-commitment.
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DOI: 10.13075/ijomeh.1896.01894
Abstract: OBJECTIVES Work-related stress (WRS) is significantly associated with health-related quality of life (HRQoL), but the amounts of evidence on differences of effort-reward imbalance (ERI) and job strain index (JSI) remain sparse and have limited generalizability.… read more here.
Keywords: health; civil servants; job; jsi ... See more keywords
Jet stream related iatrogenic retinal breaks during vitreo-retinal surgery
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DOI: 10.4103/ijo.ijo_1918_21
Abstract: Purpose: To evaluate the causes of jet stream injury (JSI)-related iatrogenic retinal breaks (IRBs) during vitreoretinal surgery (VRS). Methods: The precise surgical environment, which includes the indication and type of surgical procedure, retina status, details… read more here.
Keywords: jet stream; retinal breaks; jsi; related iatrogenic ... See more keywords