Interleukin-23 receptor gene polymorphisms in Iranian patients with juvenile systemic lupus erythematosus.
Sign Up to like & getrecommendations! Published in 2019 at "Allergologia et immunopathologia"
DOI: 10.1016/j.aller.2019.05.007
Abstract: INTRODUCTION AND OBJECTIVES Considering the possible roles of interleukin-23 receptor (IL-23R) gene in the pathogenesis of juvenile systemic lupus erythematosus (JSLE), the objective of this study was to elucidate whether polymorphisms of the IL23R are… read more here.
Keywords: systemic lupus; lupus erythematosus; jsle; gene ... See more keywords
Increased apolipoprotein-B:A1 ratio predicts cardiometabolic risk in patients with juvenile onset SLE
Sign Up to like & getrecommendations! Published in 2021 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2021.103243
Abstract: Background Cardiovascular disease is a leading cause of mortality in patients with juvenile-onset systemic lupus erythematosus (JSLE). Traditional factors for cardiovascular risk (CVR) prediction are less robust in younger patients. More reliable CVR biomarkers are… read more here.
Keywords: risk; apob apoa1; cardiometabolic risk; jsle ... See more keywords
Study of NLRP3 Single Nucleotide Polymorphisms in Juvenile Systemic Lupus Erythematosus (JSLE).
Sign Up to like & getrecommendations! Published in 2023 at "Immunological investigations"
DOI: 10.1080/08820139.2023.2215280
Abstract: Juvenile systemic lupus erythematosus (JSLE) is a multifaceted multifactorial disorder with an unclear etiopathogenesis. Environmental factors, genetic factors, and dysregulated and defective immune system responses are known to have a role in JSLE etiopathogenesis. NLRP3… read more here.
Keywords: jsle; single nucleotide; juvenile systemic; systemic lupus ... See more keywords
Subclinical Retinal Capillary Abnormalities in Juvenile Systemic Lupus Erythematosus without Ocular Involvement
Sign Up to like & getrecommendations! Published in 2022 at "Ocular Immunology and Inflammation"
DOI: 10.1080/09273948.2022.2116584
Abstract: ABSTRACT Purpose This study aimed to evaluate subclinical retinal microvascular changes with OCTA in juvenile systemic lupus erythematosus (JSLE) patients without ocular involvement. Methods Ten eyes of 10 JSLE and 13 eyes of 13 age… read more here.
Keywords: jsle; juvenile systemic; subclinical retinal; systemic lupus ... See more keywords
"It is good to have a target in mind": Qualitative views of patients and parents informing a treat to target clinical trial in JSLE.
Sign Up to like & getrecommendations! Published in 2021 at "Rheumatology"
DOI: 10.1093/rheumatology/keab173
Abstract: OBJECTIVE We sought to explore patient and parental views on treatment targets, outcome measures and study designs being considered for a future juvenile-onset systemic lupus erythematosus (JSLE) treat to target (T2T) study. METHODS Topic guided,… read more here.
Keywords: treatment; patients parents; treat target; target ... See more keywords
Anti-SARS-CoV-2 vaccination in adolescent and adult patients with juvenile onset systemic lupus erythematosus: tolerability and impact on disease activity.
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead047
Abstract: OBJECTIVES Juvenile onset systemic lupus erythematosus (jSLE) has a severe presentation and a remitting course. Patients with jSLE carry an increased vulnerability to infections, which also act as triggers of disease flare. Thus, vaccination against… read more here.
Keywords: vaccination; jsle; disease activity; cov vaccination ... See more keywords
OA40 Predicting cardiovascular disease risk in children and adolescents with juvenile-onset systemic lupus erythematosus using the APPLE (Atherosclerosis Prevention in Paediatric Lupus Erythematosus) clinical trial cohort
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead104.039
Abstract: The risk of developing cardiovascular disease (CVD) through atherosclerosis in juvenile-onset systemic lupus erythematosus (JSLE) patients is significantly increased. This study aimed to stratify and characterise JSLE patients at elevated CVD risk using patient/disease-related factors… read more here.
Keywords: lupus erythematosus; risk; jsle; cohort ... See more keywords
Current views on lupus in children
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000913
Abstract: Purpose of review This manuscript provides an update on clinical and pathophysiological features of juvenile-onset systemic lupus erythematosis (jSLE), challenges applying adult-derived classification criteria, and recent advances in treatment and care. Recent findings Significant scientific… read more here.
Keywords: lupus children; current views; development; jsle ... See more keywords
Juvenile systemic lupus erythematosus in Nigeria
Sign Up to like & getrecommendations! Published in 2017 at "Lupus"
DOI: 10.1177/0961203316672927
Abstract: Juvenile systemic lupus erythematosus (JSLE) is a complex multisystemic autoimmune disorder of unknown cause. It accounts for about one in five cases of SLE. The tendency for SLE to run a fulminant course when it… read more here.
Keywords: systemic lupus; jsle; juvenile systemic; lupus erythematosus ... See more keywords
Clinical predictors of active LN development in children – evidence from the UK JSLE Cohort Study
Sign Up to like & getrecommendations! Published in 2018 at "Lupus"
DOI: 10.1177/0961203318801526
Abstract: Background Juvenile-onset systemic lupus erythematosus (JSLE) patients may develop lupus nephritis (LN) during their initial presentation, or later in their disease. This study aimed to assess whether clinical/demographic factors characterize patients with LN within the… read more here.
Keywords: jsle; jsle cohort; development; cohort study ... See more keywords
Adequate tetanus but poor diphtheria and pertussis response to a Tdap booster in adolescents with juvenile systemic lupus erythematosus
Sign Up to like & getrecommendations! Published in 2020 at "Lupus"
DOI: 10.1177/0961203320973263
Abstract: Background Reports on vaccine responses in immunocompromised patients, such as juvenile systemic lupus erythematosus (jSLE), have shown highly variable results. Objective To compare the immune response and safety after a Tdap booster in 26 jSLE… read more here.
Keywords: pertussis; tdap booster; response; jsle ... See more keywords