Vitamin C protects against defects induced by juglone during porcine oocyte maturation
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28555
Abstract: Juglone, a naphthoquinone isolated from many species of the Juglandaceae family, has been used in traditional Chinese medicine for centuries because of its antiviral, antibacterial, and antitumor activities. However, the toxicity of juglone has also… read more here.
Keywords: oocyte maturation; juglone exposure; porcine oocyte; juglone ... See more keywords
Autophagy-related biological targets and network mechanisms of juglone against bladder cancer
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cancer Research and Clinical Oncology"
DOI: 10.1007/s00432-025-06243-5
Abstract: This study aimed to explore juglone’s mechanism in inducing autophagy and apoptosis in bladder cancer (BLCA) via network pharmacology and experimental validation. Juglone’s effects on BLCA cell proliferation, apoptosis, and autophagy were assessed using CCK-8,… read more here.
Keywords: cancer; pharmacology; autophagy; network ... See more keywords
Insecticidal effect of juglone and its disturbance analysis in metabolic profiles of Aphis gossypii glover using 1H NMR-based metabonomics approach
Sign Up to like & getrecommendations! Published in 2018 at "Phytoparasitica"
DOI: 10.1007/s12600-018-0682-6
Abstract: Juglone shows a wide range of biological activities but its insecticidal effect and mechanism on Aphis gossypii has not been reported up to now. In this study, on the basis of insecticidal effect research, a… read more here.
Keywords: insecticidal effect; aphis gossypii; analysis; juglone ... See more keywords
Investigating the interaction of juglone (5-hydroxy-1, 4-naphthoquinone) with serum albumins using spectroscopic and in silico methods
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the Iranian Chemical Society"
DOI: 10.1007/s13738-017-1094-0
Abstract: The interaction between juglone at the concentration range of 10–110 µM and bovine serum albumin (BSA) or human serum albumin (HSA) at the constant concentration of 11 µM was investigated by fluorescence and UV absorption spectroscopy under… read more here.
Keywords: interaction; juglone; albumin; interaction juglone ... See more keywords
Allelopathic inhibition of juglone (5-hydroxy-1,4-naphthoquinone) on the growth and physiological performance in Microcystis aeruginosa.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of environmental management"
DOI: 10.1016/j.jenvman.2018.11.105
Abstract: The elimination of cyanobacteria blooms has become an urgent concern in aquatic environmental protection. Allelopathic control is considered a potential approach because of its exclusive and ecological safety properties. The present study evaluated the allelopathic… read more here.
Keywords: allelopathic inhibition; juglone; microcystis aeruginosa; cell ... See more keywords
The oxidative stress in allelopathy: Participation of prenyllipid antioxidants in the response to juglone in Chlamydomonas reinhardtii.
Sign Up to like & getrecommendations! Published in 2017 at "Phytochemistry"
DOI: 10.1016/j.phytochem.2017.09.012
Abstract: Allelopathy is a phenomenon, where one species releases compounds able to inhibit the growth of other species. Juglone, 5-hydroxy-1,4-naphtoquinone, is an allelochemical produced by walnut trees. The main mode of juglone toxicity is the formation… read more here.
Keywords: participation; response juglone; juglone; prenyllipid antioxidants ... See more keywords
A comprehensive Study of Juglone's Effect on Polyphenol Oxidase in Cucumber: In Vitro Experiments and Computational Docking and Dynamics Insights.
Sign Up to like & getrecommendations! Published in 2024 at "Physiologia plantarum"
DOI: 10.1111/ppl.14420
Abstract: This study explores the impact of juglone on cucumber (Cucumis sativus cv. Beith Alpha), scrutinizing its effects on seed germination, growth, and the polyphenol oxidase (PPO) enzyme's activity and gene expression. Employing concentrations ranging from… read more here.
Keywords: polyphenol oxidase; juglone; ppo; growth ... See more keywords
In Vitro Inhibition of Helicobacter pylori Growth by Redox Cycling Phenylaminojuglones
Sign Up to like & getrecommendations! Published in 2018 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2018/1618051
Abstract: Infection by Helicobacter pylori increases 10 times the risk of developing gastric cancer. Juglone, a natural occurring 1,4-naphthoquinone, prevents H. pylori growth by interfering with some of its critical metabolic pathways. Here, we report the… read more here.
Keywords: helicobacter pylori; growth; juglone; pylori growth ... See more keywords
Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma
Sign Up to like & getrecommendations! Published in 2017 at "BMC Neurology"
DOI: 10.1186/s12883-017-0843-0
Abstract: BackgroundJuglone is a natural pigment, which has cytotoxic effect against various human tumor cells. However, its cytotoxicity to glioma cells, especially to tumor stem-like cells (TSCs) has not been demonstrated.MethodsTSCs of glioma were enriched from… read more here.
Keywords: ros p38; like cells; juglone; tumor stem ... See more keywords
Is Juglone the Only Naphthoquinone in Juglans regia L. with Allelopathic Effects?
Sign Up to like & getrecommendations! Published in 2021 at "Agriculture"
DOI: 10.3390/agriculture11080784
Abstract: We investigated whether juglone is the only allelochemical in a leaf extract from the walnut (Juglans regia L.). This was achieved through comparisons of the effects of pure juglone (1 mM, 100 μM, 10 μM… read more here.
Keywords: seed; juglans regia; juglone; control juglone ... See more keywords
Differential Effects of the Allelochemical Juglone on Growth of Harmful and Non-Target Freshwater Algae
Sign Up to like & getrecommendations! Published in 2020 at "Applied Sciences"
DOI: 10.3390/app10082873
Abstract: Allelopathy has been applied to control nuisance algae in aquatic systems, but the effects of allelochemicals on the broad spectrum of algae are not well understood. We investigate algicidal effects of the allelochemical juglone on… read more here.
Keywords: juglone; effects allelochemical; non target; growth ... See more keywords