c-Jun-mediated JMJD6 restoration enhances resistance of liver cancer to radiotherapy through the IL-4-activated ERK pathway.
Sign Up to like & getrecommendations! Published in 2023 at "Cell biology international"
DOI: 10.1002/cbin.12026
Abstract: Radiotherapy is widely used in the treatment of liver cancer, but the efficacy can be limited by radioresistance. In this study, we attempt to delineate the possible molecular mechanism of c-Jun-regulated Jumonji domain-containing protein 6/interleukin… read more here.
Keywords: erk pathway; liver cancer; jun; resistance ... See more keywords
Nonalcoholic fatty liver disease impairs expression of the type II inositol 1,4,5‐trisphosphate receptor
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.29588
Abstract: Nonalcoholic fatty liver disease (NAFLD) is the most prevalent liver disease worldwide. It may result in several types of liver problems, including impaired liver regeneration (LR), but the mechanism for this is unknown. Because LR… read more here.
Keywords: itpr2; fatty liver; jun; expression ... See more keywords
c‐Jun expression after cerebral hyperstimulation differs between rats and marmosets
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24399
Abstract: Immediate early genes (IEGs) are a fundamental element in the way we respond and adapt to a variety of stimuli. We have recently reported that IEG response, as measured by c‐Fos expression, is different between… read more here.
Keywords: jun expression; rats marmosets; cortex; jun ... See more keywords
Stimulation of Fas/FasL‐mediated apoptosis by luteolin through enhancement of histone H3 acetylation and c‐Jun activation in HL‐60 leukemia cells
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.22807
Abstract: Luteolin (3′,4′,5,7‐tetrahydroxyflavone), which exists in fruits, vegetables, and medicinal herbs, is used in Chinese traditional medicine for treating various diseases, such as hypertension, inflammatory disorders, and cancer. However, the gene‐regulatory role of luteolin in cancer… read more here.
Keywords: histone acetylation; acetylation; jun; fas fasl ... See more keywords
c-Jun promotes the survival of H9c2 cells under hypoxia via PTEN/Akt signaling pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Physiology and Biochemistry"
DOI: 10.1007/s13105-019-00695-3
Abstract: Ischemia and hypoxia are common pathophysiological characteristics in cardiovascular diseases. c-Jun expression could be induced by extra- or intracellular stimuli and plays a pivotal role in regulating cell survival in response to the stress. However,… read more here.
Keywords: h9c2 cells; akt signaling; pten akt; jun ... See more keywords
Major Pharmaceutical Conferences and Courses
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutical Medicine"
DOI: 10.1007/s40290-020-00331-2
Abstract: 01-Jun-20 03-Jun-20 11th Digital Pharma West Burlingame, CA, USA ExL Events http://www.exlev ents. com 01-Jun-20 05-Jun-20 11th Annual Biotherapeutics Analytical Summit Alexandria, VA, USA Cambridge Healthtech Institute http://www.healt htech .com 02-Jun-20 03-Jun-20 Common Technical Document… read more here.
Keywords: jun jun; jun; http www; medicine ... See more keywords
Deciphering the formation mechanism of ancient Jun wares copper red and blue glazes
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cultural Heritage"
DOI: 10.1016/j.culher.2021.01.008
Abstract: Abstract Ancient Jun ware glazes were recreated using a triangle ingredients-based approach. The formation mechanisms of different color glazes, especially the copper red and blue, were studied by X-ray diffraction (XRD), X-ray photoelectron spectrometry (XPS),… read more here.
Keywords: blue; formation; glaze; jun ... See more keywords
Protein kinase C theta (Prkcq) affects nerve degeneration and regeneration through the c-fos and c-jun pathways in injured rat sciatic nerves
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Neurology"
DOI: 10.1016/j.expneurol.2021.113843
Abstract: BACKGROUND Previous finding using DNA microarray and bioinformatics analysis, we have reported some key factors which regulated gene expression and signaling pathways in injured sciatic nerve during Wallerian Degeneration (WD). This research is focused on… read more here.
Keywords: nerve degeneration; jun; prkcq; degeneration regeneration ... See more keywords
c-Jun/Bim Upregulation in Dopaminergic Neurons Promotes Neurodegeneration in the MPTP Mouse Model of Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.12.026
Abstract: Parkinson's disease (PD) is a common neurodegenerative disease that is characterized by the progressive loss of dopaminergic neurons in the substantia nigra pars compacta (SNpc). The proapoptotic BH3-only protein Bim has been reported to be… read more here.
Keywords: mptp; jun; parkinson disease; dopaminergic neurons ... See more keywords
Multivalent Interactions with Fbw7 and Pin1 Facilitate Recognition of c-Jun by the SCFFbw7 Ubiquitin Ligase.
Sign Up to like & getrecommendations! Published in 2018 at "Structure"
DOI: 10.1016/j.str.2017.11.003
Abstract: Many regulatory proteins, including the transcription factor c-Jun, are highly enriched in disordered protein regions that govern growth, division, survival, differentiation, and response to signals. The stability of c-Jun is controlled by poorly understood regulatory… read more here.
Keywords: jun; ubiquitin ligase; interactions fbw7; multivalent interactions ... See more keywords
β-cantenin is potentially involved in the regulation of c-Jun signaling following bovine herpesvirus 1 infection
Sign Up to like & getrecommendations! Published in 2020 at "Veterinary Microbiology"
DOI: 10.1016/j.vetmic.2020.108804
Abstract: Abstract C-Jun, activated by various extracellular signals, is important for cell differentiation, proliferation, apoptosis, and inflammatory responses. We have previously reported that bovine herpesvirus 1 (BoHV-1) infection in MDBK cells stimulates the c-Jun NH2-terminal kinase… read more here.
Keywords: jun; bovine herpesvirus; infection; bohv infection ... See more keywords