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Smad7 Enhances TGF-β-Induced Transcription of c-Jun and HDAC6 Promoting Invasion of Prostate Cancer Cells

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Published in 2020 at "iScience"

DOI: 10.1016/j.isci.2020.101470

Abstract: Summary Transforming growth factor β (TGF-β) enhances migration and invasion of cancer cells, causing life-threatening metastasis. Smad7 expression is induced by TGF-β to control TGF-β signaling in a negative feedback manner. Here we report an… read more here.

Keywords: cancer; jun hdac6; smad7; prostate cancer ... See more keywords