Abstract 3925: JunB regulates expression of HPV genes in head and neck cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3925
Abstract: The incidence of HPV-positive head and neck squamous cell carcinoma (HNSCC) is now being considered an epidemic in the US and Western Europe as rates have surpassed those for cervical cancer. For approximately 14,400 patients… read more here.
Keywords: junb; hpv; expression; hpv positive ... See more keywords
Combined Targeting of Distinct c-Myc and JunB Transcriptional Programs for Multiple Myelioma Therapy
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-125202
Abstract: c-Myc plays a pivotal role in multiple myeloma (MM) pathogenesis; and the BET protein BRD4 is a key regulator of c-Myc transcription. Recently, a pathophysiologic role in MM has also been attributed to the AP-1… read more here.
Keywords: transcriptional programs; protein levels; myc junb; junb ... See more keywords
Dissecting Immunosuppressive Cell Communication Patterns Reveals JunB Proto-Oncogene (JUNB) Shaping a Non-Inflamed Tumor Microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.883583
Abstract: Background: Immunosuppressive cell interactions are responsible for tumor progression and metastasis, as well as anti-tumor immune dysfunction. However, the communication pattern remains unclear. Methods: We first integrated two single-cell RNA-seq datasets (GSE72056 and GSE103322) of… read more here.
Keywords: junb; communication; immunosuppressive cell; tumor ... See more keywords