An agonist of a zinc‐sensing receptor GPR39 enhances tight junction assembly in intestinal epithelial cells via an AMPK‐dependent mechanism
Sign Up to like & getrecommendations! Published in 2019 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.10.038
Abstract: Abstract Intestinal barrier function depends on integrity of tight junctions, which serve as barriers to transepithelial influx of noxious substances/microorganisms from gut lumen. The G‐protein coupled receptor 39 (GPR39) is a zinc‐sensing receptor, which is… read more here.
Keywords: zinc; gpr39; junction assembly; receptor ... See more keywords
Regulation of Tjp1 mRNA by CPEB2 for tight junction assembly in mouse blastocyst.
Sign Up to like & getrecommendations! Published in 2022 at "Reproduction"
DOI: 10.1530/rep-21-0227
Abstract: Cytoplasmic polyadenylation element binding protein 2 (CPEB2) is an mRNA-binding protein that regulates the cytoplasmic polyadenylation of mRNA and is required for tight junction (TJ) assembly in the trophectoderm epithelium during porcine preimplantation development. However,… read more here.
Keywords: tjp1 mrna; tight junction; cpeb2; junction assembly ... See more keywords