HIV‐1 Tat‐induced bystander apoptosis in Jurkat cells involves unfolded protein responses
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3357
Abstract: The HIV transactivator protein (Tat) is a multifunctional protein that plays a critical role in viral replication and contributes to several pathological symptoms of HIV‐1 infection, which has the loss of CD4+ T lymphocytes as… read more here.
Keywords: jurkat; apoptosis jurkat; unfolded protein; jurkat cells ... See more keywords
Synergistic Effect of TPD7 and Berberine against Leukemia Jurkat Cell Growth through Regulating Ephrin‐B2 Signaling
Sign Up to like & getrecommendations! Published in 2017 at "Phytotherapy Research"
DOI: 10.1002/ptr.5866
Abstract: TPD7, a novel biphenyl urea taspine derivative, and berberine have presented inhibition on VEGFR2 that can be regulated by ephrin‐B2 reverse signaling through interactions with the PDZ domain. The purpose of this study is to… read more here.
Keywords: jurkat; tpd7 berberine; cell; leukemia ... See more keywords
Landfill soil leachates from Nigeria and India induced DNA damage and alterations in genes associated with apoptosis in Jurkat cell
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Science and Pollution Research"
DOI: 10.1007/s11356-021-15985-x
Abstract: Landfill soil leachates, containing myriad of xenobiotics, increase genotoxic and cytotoxic stress–induced cell death. However, the underlying mechanism involved in the elimination of the damaged cells is yet to be fully elucidated. This study investigated… read more here.
Keywords: apoptosis; soil leachates; landfill soil; jurkat ... See more keywords
Tetrandrine and cepharanthine induce apoptosis through caspase cascade regulation, cell cycle arrest, MAPK activation and PI3K/Akt/mTOR signal modification in glucocorticoid resistant human leukemia Jurkat T cells.
Sign Up to like & getrecommendations! Published in 2019 at "Chemico-biological interactions"
DOI: 10.1016/j.cbi.2019.108726
Abstract: Tetrandrine (TET) and cepharanthine (CEP) are two bisbenzylisoquinoline alkaloids isolated from the traditional herbs. Recent molecular investigations firmly supported that TET or CEP would be a potential candidate for cancer chemotherapy. Prognosis of patients with… read more here.
Keywords: cep; tet cep; glucocorticoid resistant; jurkat ... See more keywords
RNAi-mediated knockdown of VDR surprisingly suppresses cell growth in Jurkat T and U87-MG cells
Sign Up to like & getrecommendations! Published in 2019 at "Heliyon"
DOI: 10.1016/j.heliyon.2019.e02837
Abstract: Vitamin D receptor (VDR) is a nuclear receptor for 1,25-Dihydroxyvitamin D3. VDR is expressed in many types of cells and involved in different biological processes such as immunity and inflammation. In addition, the role for… read more here.
Keywords: vdr; cell lines; cell growth; jurkat ... See more keywords
Interaction of Zap70 and CXCR4 receptor at lamellipodia that determines the directionality during Jurkat T cells chemotaxis.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular immunology"
DOI: 10.1016/j.molimm.2017.08.005
Abstract: Directional migration of T-lymphocytes is a key process during immune activation and is tightly regulated both temporally and spatially. The initial cell membrane protrusion at a particular site is critical for determining the direction of… read more here.
Keywords: lamellipodia; jurkat cells; jurkat; zap ... See more keywords
Evaluation of the mechanism of anticancer activity of deltamethrin in Jurkat-J6 cell line.
Sign Up to like & getrecommendations! Published in 2018 at "Pesticide biochemistry and physiology"
DOI: 10.1016/j.pestbp.2018.06.010
Abstract: Deltamethrin (DLM) is an α-cyano type-II synthetic pyrethroid compound which is extensively used in different agricultural and home pest control. The advantages of pyrethroids over other insecticides are that they are relatively non-toxic to birds… read more here.
Keywords: cell line; mechanism; jurkat; cell ... See more keywords
Immunotherapy Study on Non-small-Cell Lung Cancer (NSCLC) Combined with Cytotoxic T Cells and miRNA34a
Sign Up to like & getrecommendations! Published in 2024 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.3c01040
Abstract: Immunotherapy has emerged as a promising approach for cancer treatment, and the use of microRNAs (miRNAs) as therapeutic agents has gained significant attention. In this study, we investigated the effectiveness of immunotherapy utilizing miRNA34a and… read more here.
Keywords: cancer; non small; cancer cells; jurkat ... See more keywords
Induction of caspase-2 gene expression in carboxyl-functionalized carbon nanotube-treated human T-cell leukemia (Jurkat) cell line
Sign Up to like & getrecommendations! Published in 2019 at "Drug and Chemical Toxicology"
DOI: 10.1080/01480545.2019.1609025
Abstract: Abstract Carbon nanotubes (CNTs) have great potential as novel diagnostic or therapeutic tools in biomedicine but, cellular toxicity must be well considered before widespread application of CNTs. Many chemical agents exert their toxicity through apoptotic… read more here.
Keywords: gene expression; expression; jurkat; carboxyl functionalized ... See more keywords
PO-320 Anti-inflammatory effects of gossypol on human lymphocytic jurkat cells via regulation of MAPK signalling and cell cycle
Sign Up to like & getrecommendations! Published in 2018 at "ESMO Open"
DOI: 10.1136/esmoopen-2018-eacr25.833
Abstract: Introduction Gossypol, a natural polyphenolic compound extracted from the cotton seed oil, have been reported to possess pharmacological properties via modulation of cell cycle and immune signalling pathway. However, whether gossypol has anti-inflammatory effects against… read more here.
Keywords: anti inflammatory; cell cycle; jurkat cells; jurkat ... See more keywords
Phagocytosis of LM-Mel-45 Melanoma and Jurkat Cells by THP-1 Macrophages
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5733764
Abstract: Exposing macrophages to IFN-g or IL-4 polarizes them toward M1-like inflammatory or M2-like tissue repair phenotypes, respectively. It is uncertain whether the macrophage phenotypes are equally effective at phagocytosing melanoma and non-melanoma bait cells. We… read more here.
Keywords: jurkat cells; melanoma; phagocytosis; jurkat ... See more keywords