Genetic mutations in Ca2+ signaling alter dendrite morphology and social approach in juvenile mice
Sign Up to like & getrecommendations! Published in 2019 at "Genes"
DOI: 10.1111/gbb.12526
Abstract: Dendritic morphology is a critical determinant of neuronal connectivity, and calcium signaling plays a predominant role in shaping dendrites. Altered dendritic morphology and genetic mutations in calcium signaling are both associated with neurodevelopmental disorders (NDDs).… read more here.
Keywords: juvenile mice; morphology; dendritic morphology; mice ... See more keywords
Long-acting PDE5 inhibitor tadalafil prevents early doxorubicin-induced left ventricle diastolic dysfunction in juvenile mice: potential role of cytoskeletal proteins.
Sign Up to like & getrecommendations! Published in 2017 at "Canadian journal of physiology and pharmacology"
DOI: 10.1139/cjpp-2016-0551
Abstract: The chemotherapeutic use of doxorubicin (Dox) is hindered due to the development of irreversible cardiotoxicity. Specifically, childhood cancer survivors are at greater risk of Dox-induced cardiovascular complications. Because of the potent cardioprotective effect of phosphodiesterase… read more here.
Keywords: juvenile mice; pde5; treatment; dox treatment ... See more keywords
Early Low-Level Arsenic Exposure Impacts Post-Synaptic Hippocampal Function in Juvenile Mice
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DOI: 10.3390/toxics9090206
Abstract: Arsenic is a well-established carcinogen known to increase mortality, but its effects on the central nervous system are less well understood. Epidemiological studies suggest that early life exposure is associated with learning deficits and behavioral… read more here.
Keywords: juvenile mice; synaptic transmission; exposure; arsenic exposure ... See more keywords
Effects of applying amoxicillin in juvenile mice on enamel mineralization and the expression of kallikrein-related peptidase 4 and tight junction proteins in ameloblasts
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DOI: 10.3892/ijmm.2020.4598
Abstract: Amoxicillin is a common pediatric drug. However, to the best of our knowledge, the role of amoxicillin in enamel hypomineralization has not yet been fully elucidated. The aim of the present study was to assess… read more here.
Keywords: juvenile mice; amoxicillin; expression; enamel ... See more keywords