Abnormal gait and motor cortical processing in drug‐resistant juvenile myoclonic epilepsy
Sign Up to like & getrecommendations! Published in 2023 at "Brain and Behavior"
DOI: 10.1002/brb3.2872
Abstract: Juvenile myoclonic epilepsy (JME) is characterized by generalized seizures. Nearly 30% of JME patients are drug‐resistant (DR‐JME), indicating a widespread cortical dysfunction. Walking is an important function that necessitates orchestrated coordination of frontocentral cortical regions.… read more here.
Keywords: juvenile myoclonic; myoclonic epilepsy; gait motor; drug resistant ... See more keywords
EFHC1 mutation in Indian juvenile myoclonic epilepsy patient
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DOI: 10.1002/epi4.12037
Abstract: Juvenile myoclonic epilepsy (JME) is the most common form of idiopathic generalized epilepsies (IGEs) and is genetically heterogeneous. Mutations in EFHC1 cause JME. Because about 2 million people in India are affected by JME alone,… read more here.
Keywords: jme; myoclonic epilepsy; efhc1 mutation; juvenile myoclonic ... See more keywords
P11-S Co-existence of Juvenile Myoclonic Epilepsy and Neurofibromatosis and the lessons learned from one case report
Sign Up to like & getrecommendations! Published in 2019 at "Clinical Neurophysiology"
DOI: 10.1016/j.clinph.2019.04.551
Abstract: Background Neurofibromatosis type 1 (NF1) is a common autosomal dominant disorder, afflicting 1 in 2500–3000 individuals. These patients harbor cafe-au-lait macules, axillary and inguinal freckling, neurofibromas and optic pathway gliomas. Epilepsy, although not usual, is… read more here.
Keywords: epilepsy; juvenile myoclonic; case; myoclonic epilepsy ... See more keywords
Alteration of cerebello‐thalamocortical spontaneous low‐frequency oscillations in juvenile myoclonic epilepsy
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neurologica Scandinavica"
DOI: 10.1111/ane.13138
Abstract: Altered thalamocortical network has been proposed to play a pivotal role in the principal pathophysiology underlying juvenile myoclonic epilepsy (JME). Recently, resting‐state fMRI studies have provided converging evidence for thalamocortical dysconnectivity in patients with JME.… read more here.
Keywords: frequency oscillations; spontaneous low; juvenile myoclonic; frequency ... See more keywords
DNA methylation of the BRD2 promoter is associated with juvenile myoclonic epilepsy in Caucasians
Sign Up to like & getrecommendations! Published in 2018 at "Epilepsia"
DOI: 10.1111/epi.14058
Abstract: Juvenile myoclonic epilepsy (JME) is a common adolescent‐onset genetic generalized epilepsy (GGE) syndrome. Multiple linkage and association studies have found that BRD2 influences the expression of JME. The BRD2‐JME connection is further corroborated by our… read more here.
Keywords: juvenile myoclonic; brd2; myoclonic epilepsy; promoter ... See more keywords
Efficacy of levetiracetam, lamotrigine and sodium valproate on seizure attacks and EEG disorders in patients with juvenile myoclonic epilepsy: A double blind randomized clinical trial
Sign Up to like & getrecommendations! Published in 2022 at "Caspian Journal of Internal Medicine"
DOI: 10.22088/cjim.13.3.617
Abstract: Background: Juvenile myoclonic epilepsy (JME) is one of the most important types of generalized idiopathic epilepsy. Patients generally respond quickly and perfectly to standard antiepileptic drugs but lifelong medication is necessary. Sodium valproate is the… read more here.
Keywords: valproate; sodium valproate; efficacy; epilepsy ... See more keywords
Development and Validation of MRI-Based Radiomics Models for Diagnosing Juvenile Myoclonic Epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Korean Journal of Radiology"
DOI: 10.3348/kjr.2022.0539
Abstract: Objective Radiomic modeling using multiple regions of interest in MRI of the brain to diagnose juvenile myoclonic epilepsy (JME) has not yet been investigated. This study aimed to develop and validate radiomics prediction models to… read more here.
Keywords: gradient boosting; juvenile myoclonic; myoclonic epilepsy; boosting machine ... See more keywords
Drug-Resistant Juvenile Myoclonic Epilepsy: Misdiagnosis of Progressive Myoclonus Epilepsy
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2019.00946
Abstract: Juvenile myoclonic epilepsy (JME) is a common epilepsy syndrome characterized by bilateral myoclonic and tonic-clonic seizures typically starting in adolescence and responding well to medication. Misdiagnosis of a more severe progressive myoclonus epilepsy (PME) as… read more here.
Keywords: epilepsy; juvenile myoclonic; drug; drug resistant ... See more keywords
Neurophysiological and Genetic Findings in Patients With Juvenile Myoclonic Epilepsy
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Integrative Neuroscience"
DOI: 10.3389/fnint.2020.00045
Abstract: Objective Transcranial magnetic stimulation (TMS), a non-invasive procedure, stimulates the cortex evaluating the central motor pathways. The response is called motor evoked potential (MEP). Polyphasia results when the response crosses the baseline more than twice… read more here.
Keywords: epilepsy; juvenile myoclonic; analysis; polyphasia ... See more keywords
Can Disruption of Basal Ganglia-Thalamocortical Circuit in Wilson Disease Be Associated with Juvenile Myoclonic Epilepsy Phenotype?
Sign Up to like & getrecommendations! Published in 2022 at "Brain Sciences"
DOI: 10.3390/brainsci12050553
Abstract: In this paper, we describe the multimodal MRI findings in a patient with Wilson disease and a seizure disorder, characterized by an electroclinical picture resembling juvenile myoclonic epilepsy. The brain structural MRI showed a deposition… read more here.
Keywords: basal ganglia; juvenile myoclonic; myoclonic epilepsy; wilson disease ... See more keywords
Omitting Hyperventilation in Electroencephalogram during the COVID-19 Pandemic May Reduce Interictal Epileptiform Discharges in Patients with Juvenile Myoclonic Epilepsy
Sign Up to like & getrecommendations! Published in 2022 at "Brain Sciences"
DOI: 10.3390/brainsci12060769
Abstract: Background: To prevent the spread of coronavirus disease 2019 (COVID-19), hyperventilation (HV) activation has been avoided in electroencephalograms (EEGs) since April 2020. The influence of omitting HV in EEG on epilepsy diagnosis remains uncertain for… read more here.
Keywords: epileptiform discharges; eeg; epilepsy; juvenile myoclonic ... See more keywords