Topovectorial mechanisms control the juxtamembrane proteolytic processing of Nrf1 to remove its N‐terminal polypeptides during maturation of the CNC‐bZIP factor
Sign Up to like & getrecommendations! Published in 2018 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2018.09.039
Abstract: &NA; The topobiological behaviour of Nrf1 dictates its post‐translational modification and its ability to transactivate target genes. Here, we have elucidated that topovectorial mechanisms control the juxtamembrane processing of Nrf1 on the cyto/nucleoplasmic side of… read more here.
Keywords: topovectorial mechanisms; juxtamembrane; mechanisms control; proteolytic processing ... See more keywords
A juxtamembrane basolateral targeting motif regulates signaling through a TGF-β pathway receptor in Drosophila
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DOI: 10.1371/journal.pbio.3001660
Abstract: In polarized epithelial cells, receptor–ligand interactions can be restricted by different spatial distributions of the 2 interacting components, giving rise to an underappreciated layer of regulatory complexity. We explored whether such regulation occurs in the… read more here.
Keywords: basolateral targeting; targeting motif; punt; type ... See more keywords