HDAC6 deficiency induces apoptosis in mesenchymal stem cells through p53 K120 acetylation.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.10.087
Abstract: The acetylation of p53 is critical in modulating its pro-apoptotic roles. However, its regulatory mechanism and physiological significance are unclear. Here, we show HDAC6 negatively regulates pro-apoptotic acetylation of p53 at lysine residue 120 (K120) in… read more here.
Keywords: acetylation; k120 acetylation; hdac6; p53 ... See more keywords