K27‐linked noncanonic ubiquitination in immune regulation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Leukocyte Biology"
DOI: 10.1002/jlb.4ru0620-397rr
Abstract: Ubiquitination is a common form of posttranslational modification that has been implicated in regulating considerable immune signaling pathways. The functions of canonic K48‐ and K63‐linked ubiquitination have been well studied. However, the roles of noncanonic… read more here.
Keywords: noncanonic ubiquitination; k27 linked; linked ubiquitination; linked noncanonic ... See more keywords
Semi-synthesis of K27-linked-mixed-triubiquitin chains through a combination of enzymatic reaction with CAACU strategy
Sign Up to like & getrecommendations! Published in 2021 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2021.153000
Abstract: Abstract Atypical ubiquitin (Ub) chains were reported to be involved in certain significant cellular processes. The development of effective methods to acquire atypical Ub chains would facilitate the deciphering of Ub-mediated processes. Herein, we reported… read more here.
Keywords: k27 linked; strategy; linked mixed; caacu strategy ... See more keywords
Targeting E3 Ubiquitin Ligase WWP1 Prevents Cardiac Hypertrophy Through Destabilizing DVL2 via Inhibition of K27-Linked Ubiquitination
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DOI: 10.1161/circulationaha.121.054827
Abstract: Supplemental Digital Content is available in the text. Background: Without adequate treatment, pathological cardiac hypertrophy induced by sustained pressure overload eventually leads to heart failure. WWP1 (WW domain–containing E3 ubiquitin protein ligase 1) is an… read more here.
Keywords: hypertrophy; k27 linked; wwp1; heart ... See more keywords