An Extended Conformation for K48 Ubiquitin Chains Revealed by the hRpn2:Rpn13:K48-Diubiquitin Structure.
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DOI: 10.1016/j.str.2020.02.007
Abstract: Rpn13/Adrm1 is recruited to the proteasome by PSMD1/Rpn2, where it serves as a substrate receptor that binds preferentially to K48-linked ubiquitin chains, an established signal for protein proteolysis. Here, we use NMR to solve the… read more here.
Keywords: k48; conformation; structure; k48 diubiquitin ... See more keywords