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Published in 2022 at "Biomedical journal"
DOI: 10.1016/j.bj.2022.02.002
Abstract: BACKGROUND K63-linked polyubiquitination of proteins have nonproteolytic functions and regulate the activity of many signal transduction pathways. USP7, a HIF1α deubiquitinase, undergoes K63-linked polyubiquitination under hypoxia. K63-polyubiquitinated USP7 serves as a scaffold to anchor HIF1α,…
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Keywords:
organ defects;
polyubiquitinated usp7;
k63 polyubiquitinated;
role ... See more keywords