Articles with "k63 polyubiquitinated" as a keyword



Photo by smallcamerabigpictures from unsplash

Organ defects of the Usp7K444R mutant mouse strain indicate the essential role of K63-polyubiquitinated Usp7 in organ formation.

Sign Up to like & get
recommendations!
Published in 2022 at "Biomedical journal"

DOI: 10.1016/j.bj.2022.02.002

Abstract: BACKGROUND K63-linked polyubiquitination of proteins have nonproteolytic functions and regulate the activity of many signal transduction pathways. USP7, a HIF1α deubiquitinase, undergoes K63-linked polyubiquitination under hypoxia. K63-polyubiquitinated USP7 serves as a scaffold to anchor HIF1α,… read more here.

Keywords: organ defects; polyubiquitinated usp7; k63 polyubiquitinated; role ... See more keywords