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Functional Analysis of P450 Monooxygenase SrrO in the Biosynthesis of Butenolide-Type Signaling Molecules in Streptomyces rochei

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Published in 2020 at "Biomolecules"

DOI: 10.3390/biom10091237

Abstract: Streptomyces rochei 7434AN4 produces two structurally unrelated polyketide antibiotics lankacidin and lankamycin, and their biosynthesis is tightly controlled by butenolide-type signaling molecules SRB1 and SRB2. SRBs are synthesized by SRB synthase SrrX, and induce lankacidin… read more here.

Keywords: biosynthesis; srb1; analysis; streptomyces rochei ... See more keywords