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Published in 2021 at "Chemical Science"
DOI: 10.1039/d1sc03222d
Abstract: An effective catalyst has been developed for the three-component reaction of aldehydes, anilines and phosphites in an asymmetric catalytic Kabachnik–Fields reaction to give α-aminophosphonates. A catalyst was sought that would give high asymmetric inductions for…
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Keywords:
kabachnik fields;
zirconium catalyzed;
catalyst;
aliphatic aldehydes ... See more keywords
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Published in 2022 at "Materials"
DOI: 10.3390/ma15113846
Abstract: We reported a new method dealing with the synthesis of novel pharmacologically relevant α-aminophosphonate derivatives via a lipase-catalyzed Kabachnik−Fields reaction with yields of up to 93%. The advantages of this protocol are excellent yields, mild…
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Keywords:
kabachnik fields;
lipase catalyzed;
aminophosphonate derivatives;
catalyzed kabachnik ... See more keywords
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Published in 2021 at "Molecules"
DOI: 10.3390/molecules26092511
Abstract: The Kabachnik–Fields reaction, comprising the condensation of an amine, oxo compound and a P-reagent (generally a >P(O)H species or trialkyl phosphite), still attracts interest due to the challenging synthetic procedures and the potential biological activity…
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Keywords:
kabachnik fields;
synthesis aminophosphonates;
last decade;
fields reaction ... See more keywords