Axonal sprouting in commissurally projecting parvalbumin‐expressing interneurons
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24011
Abstract: Previous research has shown that in vivo on‐demand optogenetic stimulation of inhibitory interneurons expressing parvalbumin (PV) is sufficient to suppress seizures in a mouse model of temporal lobe epilepsy (TLE). Surprisingly, this intervention was capable… read more here.
Keywords: expressing interneurons; commissurally projecting; axonal sprouting; parvalbumin ... See more keywords
Regulation of the Serotonergic System by Kainate in the Avian Retina
Sign Up to like & getrecommendations! Published in 2019 at "Cellular and Molecular Neurobiology"
DOI: 10.1007/s10571-019-00701-8
Abstract: Serotonin (5-HT) has been recognized as a neurotransmitter in the vertebrate retina, restricted mainly to amacrine and bipolar cells. It is involved with synaptic processing and possibly as a mitogenic factor. We confirm that chick… read more here.
Keywords: regulation serotonergic; avian retina; receptor; retina ... See more keywords
NETO1 Regulates Postsynaptic Kainate Receptors in CA3 Interneurons During Circuit Maturation
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Neurobiology"
DOI: 10.1007/s12035-019-1612-4
Abstract: Kainate type ionotropic glutamate receptors (KARs) are expressed in hippocampal interneurons and regulate interneuron excitability and GABAergic transmission. Neuropilin tolloid-like proteins (NETO1 and NETO2) act as KAR auxiliary subunits; however, their significance for various functions… read more here.
Keywords: regulates postsynaptic; ca3 interneurons; neto1 regulates; kar ... See more keywords
Organic Kainate Single Crystals for Second-Harmonic and Broadband THz Generation
Sign Up to like & getrecommendations! Published in 2023 at "ACS Applied Materials & Interfaces"
DOI: 10.1021/acsami.2c18454
Abstract: Organic crystals with unique nonlinear optical properties have been attracting attention owing to their capability to outperform their conventional nonorganic counterparts. Since nonlinear material responses are linked to a crystal’s internal microscopic structure, molecular engineering… read more here.
Keywords: single crystals; kainate; thz; second harmonic ... See more keywords
Spinal microRNA-134-5p targets glutamate receptor ionotropic kainate 3 to modulate opioid induced hyperalgesia in mice.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pain"
DOI: 10.1177/17448069231178271
Abstract: Background: Fentanyl and its analogs are extensively used for pain relief. However, their paradoxically pronociceptive effects often lead to increased opioids consumption and risk of chronic pain. Compared to other synthetic opioids, remifentanil has been… read more here.
Keywords: kainate; mir 134; glutamate receptor; induced hyperalgesia ... See more keywords
Clmp Regulates AMPA and Kainate Receptor Responses in the Neonatal Hippocampal CA3 and Kainate Seizure Susceptibility in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Synaptic Neuroscience"
DOI: 10.3389/fnsyn.2020.567075
Abstract: Synaptic adhesion molecules regulate synapse development through trans-synaptic adhesion and assembly of diverse synaptic proteins. Many synaptic adhesion molecules positively regulate synapse development; some, however, exert negative regulation, although such cases are relatively rare. In… read more here.
Keywords: susceptibility; adhesion; hippocampal ca3; mice ... See more keywords
Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158797
Abstract: Kainate receptors belong to the family of glutamate receptors ion channels, which are responsible for the majority of rapid excitatory synaptic transmission in the central nervous system. The therapeutic potential of kainate receptors is still… read more here.
Keywords: kainate; receptor subtype; kainate receptor; gluk3 kainate ... See more keywords
Structural Arrangement Produced by Concanavalin A Binding to Homomeric GluK2 Receptors
Sign Up to like & getrecommendations! Published in 2021 at "Membranes"
DOI: 10.3390/membranes11080613
Abstract: Kainate receptors are members of the ionotropic glutamate receptor family. They form cation-specific transmembrane channels upon binding glutamate that desensitize in the continued presence of agonists. Concanavalin A (Con-A), a lectin, stabilizes the active open-channel… read more here.
Keywords: dimer interface; kainate receptor; gluk2; receptor ... See more keywords