Sign Up to like & get
recommendations!
1
Published in 2022 at "Neuropsychopharmacology Reports"
DOI: 10.1002/npr2.12284
Abstract: Depression is a common disorder that affects patients' quality of life and incurs health system costs. Due to the resistance to treat depression, better understanding of neurophysiology was considered; one of the implications is the…
read more here.
Keywords:
topiramate kainate;
antagonists depression;
depression systematic;
kainate receptor ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2019 at "ACS Chemical Neuroscience"
DOI: 10.2210/pdb6fz4/pdb
Abstract: Among the ionotropic glutamate receptors, the physiological role of kainate receptors is less well understood. Although ligands with selectivity toward the kainate receptor subtype GluK1 are available, tool compounds with selectivity at the remaining kainate…
read more here.
Keywords:
kainate receptor;
quinoxaline diones;
affinity;
structure ... See more keywords
Sign Up to like & get
recommendations!
0
Published in 2019 at "Scientific Reports"
DOI: 10.2210/pdb6jfy/pdb
Abstract: GluK3-kainate receptors are atypical members of the iGluR family that reside at both the pre- and postsynapse and play a vital role in the regulation of synaptic transmission. For a better understanding of structural changes…
read more here.
Keywords:
kainate receptor;
receptor;
functional insights;
structural functional ... See more keywords
Sign Up to like & get
recommendations!
2
Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23158797
Abstract: Kainate receptors belong to the family of glutamate receptors ion channels, which are responsible for the majority of rapid excitatory synaptic transmission in the central nervous system. The therapeutic potential of kainate receptors is still…
read more here.
Keywords:
kainate;
receptor subtype;
kainate receptor;
gluk3 kainate ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2021 at "Membranes"
DOI: 10.3390/membranes11080613
Abstract: Kainate receptors are members of the ionotropic glutamate receptor family. They form cation-specific transmembrane channels upon binding glutamate that desensitize in the continued presence of agonists. Concanavalin A (Con-A), a lectin, stabilizes the active open-channel…
read more here.
Keywords:
dimer interface;
kainate receptor;
gluk2;
receptor ... See more keywords