Kaiso phosphorylation at threonine 606 leads to its accumulation in the cytoplasm, reducing its transcriptional repression of the tumour suppressor CDH1
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DOI: 10.1002/1878-0261.13292
Abstract: It is well known that the Kaiso protein (encoded by the ZBTB33 gene) is a transcription factor, and Kaiso–P120ctn [P120 catenin (CTNND1)] interaction increases the translocation of Kaiso from the nucleus into the cytoplasm. However,… read more here.
Keywords: accumulation cytoplasm; kaiso; kaiso phosphorylation; pt606 kaiso ... See more keywords
A 5′-Flanking C/G Pair at the Core Region Enhances the Recognition and Binding of Kaiso to Methylated DNA
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DOI: 10.1021/acs.jcim.2c01294
Abstract: Methyl CpG binding proteins (MBPs) are transcription factors that recognize the methylated CpG sites in DNA and mediate the DNA methylation signal into various downstream cellular processes. The C2H2 zinc finger (ZF) protein, Kaiso, also… read more here.
Keywords: recognition; pair; kaiso; methylated dna ... See more keywords
Abstract 1525: Kaiso influences immune signaling of breast cancer exosomes
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DOI: 10.1158/1538-7445.am2019-1525
Abstract: Introduction: Exosomes are communication vesicles between tumor cells and immune cells. However, the mechanism underlining this cell-cell communication is not well understanding, particularly in African American (AA) breast cancer patients. Kaiso, a bi-modal transcription factor… read more here.
Keywords: cancer; breast cancer; cancer exosomes; kaiso ... See more keywords