Dermoscopic features of post kala azar dermal leishmaniasis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.17222
Abstract: Post kala azar dermal leishmaniasis (PKDL) is a well-known sequela of visceral leishmaniasis (VL) developing either spontaneously or after treatment. Clinical presentation of PKDL include facial erythema, discrete papules, hypopigmented macules, or nodular lesions which… read more here.
Keywords: kala azar; leishmaniasis; post kala; dermoscopic features ... See more keywords
Treating murine Kala‐azar with a Mayan plant induces immunochemical changes
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DOI: 10.1111/pim.12495
Abstract: Pentalinon andrieuxii Muell Arg is a Mexican‐Central American plant anciently used by local people to treat cutaneous leishmaniasis. We evaluated a hexane extract of the root we called PAE for its chemical content and for… read more here.
Keywords: kala azar; plant; acid ethyl; ethyl ester ... See more keywords
LEISH2b - A phase 2b study to assess the safety, efficacy, and immunogenicity of the Leishmania vaccine ChAd63-KH in post-kala azar dermal leishmaniasis
Sign Up to like & getrecommendations! Published in 2022 at "Wellcome Open Research"
DOI: 10.12688/wellcomeopenres.17951.1
Abstract: Background: The leishmaniases are neglected tropical diseases caused by various Leishmania parasite species transmitted by sand flies. They comprise a number of systemic and cutaneous syndromes including kala-azar (visceral leishmaniasis, VL), cutaneous leishmaniasis (CL), and… read more here.
Keywords: kala azar; chad63; pkdl; leishmaniasis ... See more keywords
A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH
Sign Up to like & getrecommendations! Published in 2017 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0005527
Abstract: Background Visceral leishmaniasis (VL or kala azar) is the most serious form of human leishmaniasis, responsible for over 20,000 deaths annually, and post kala azar dermal leishmaniasis (PKDL) is a stigmatizing skin condition that often… read more here.
Keywords: kala azar; trial; leishmaniasis; third generation ... See more keywords
Improved kala-azar case management through implementation of health facility-based sentinel sites surveillance system in Bihar, India
Sign Up to like & getrecommendations! Published in 2021 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0009598
Abstract: Background Visceral leishmaniasis (VL), also known as kala-azar (KA), is a neglected vector-borne disease, targeted for elimination, but several affected blocks of Bihar are posing challenges with the high incidence of cases, and moreover, the… read more here.
Keywords: surveillance system; kala azar; sentinel sites; surveillance ... See more keywords
Evaluation of Recombinase Polymerase Amplification assay for monitoring parasite load in patients with kala-azar and post kala-azar dermal leishmaniasis
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0011231
Abstract: Background The potential reservoirs of visceral leishmaniasis (VL) in South Asia include asymptomatic and relapsed cases of VL, along with patients with post kala-azar dermal leishmaniasis (PKDL). Accordingly, accurate estimation of their parasite load is… read more here.
Keywords: polymerase; parasite load; kala azar; treatment ... See more keywords
BLIMP-1 Mediated Downregulation of TAK1 and p53 Molecules Is Crucial in the Pathogenesis of Kala-Azar
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.594431
Abstract: Precise regulation of inflammasome is critical during any pathogenic encounter. The whole innate immune system comprising of pattern recognition receptors (PRRs) relies on its ability to sense microbes. The fate of cellular death in infected… read more here.
Keywords: kala azar; tak1 p53; blimp mediated;
Mechanisms of Immunopathogenesis in Cutaneous Leishmaniasis And Post Kala-azar Dermal Leishmaniasis (PKDL)
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.685296
Abstract: Leishmaniasis is a neglected tropical disease that affects 12 million people worldwide. The disease has high morbidity and mortality rates and is prevalent in over 80 countries, leaving more than 300 million people at risk… read more here.
Keywords: kala azar; leishmaniasis; post kala; leishmaniasis post ... See more keywords
A Case Report of Two Kala-Azar Cases in China Diagnosed by Metagenomic Next-Generation Sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.922894
Abstract: Background Leishmaniasis being a local disease, as kala-azar this particular form is a visceral form. It is transmitted by sandflies, and is a parasitic disease involving the reticuloendothelial system of mononuclear macrophages. Due to its… read more here.
Keywords: kala; report; detection; kala azar ... See more keywords
Immune Responses in Post Kala-azar Dermal Leishmaniasis
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Dermatology"
DOI: 10.4103/ijd.ijd_258_20
Abstract: Kala-azar, commonly known as visceral leishmaniasis (VL), is a neglected tropical disease that has been targeted in South Asia for elimination by 2020. Presently, the Kala-azar Elimination Programme is aimed at identifying new low-endemic foci… read more here.
Keywords: dermal leishmaniasis; kala azar; post kala; immune responses ... See more keywords
Histopathology of Post Kala-azar Dermal Leishmaniasis
Sign Up to like & getrecommendations! Published in 2020 at "Indian Journal of Dermatology"
DOI: 10.4103/ijd.ijd_307_19
Abstract: The various lesions seen in the clinical presentation of post kala-azar dermal leishmaniasis (PKDL) are reflected in the histopathology of the type of lesion biopsied. The cells that form the dermal infiltrate include lymphocytes, histiocytes,… read more here.
Keywords: kala azar; dermal leishmaniasis; post kala; pkdl ... See more keywords