Clinical significance of kallikrein 5 as a novel prognostic biomarker in gastric adenocarcinoma
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DOI: 10.1002/jcla.23958
Abstract: Gastric cancer is one of the most common cancers with unsatisfied prognosis. It is challenging to predict gastric cancer prognosis due to its highly heterogeneous nature. Kallikrein 5 (KLK5) belongs to the family of kallikreins,… read more here.
Keywords: gastric adenocarcinoma; kallikrein; clinical significance; novel prognostic ... See more keywords
Discovery and development of plasma kallikrein inhibitors for multiple diseases.
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DOI: 10.1016/j.ejmech.2020.112137
Abstract: Plasma kallikrein (PKal) belongs to the family of trypsin-like serine proteases. The expression of PKal is associated with multiple physiological systems or pathways such as coagulation pathway, platelet aggregation process, kallikrein-kinin system, renin-angiotensin system and… read more here.
Keywords: kallikrein; discovery development; pkal inhibitors; plasma kallikrein ... See more keywords
Kallikrein-related peptidase 14 is the second KLK protease targeted by the serpin vaspin
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DOI: 10.1515/hsz-2018-0108
Abstract: Abstract Kallikrein-related peptidases KLK5, KLK7 and KLK14 are important proteases in skin desquamation and aberrant KLK activity is associated with inflammatory skin diseases such as Netherton syndrome but also with various serious forms of cancer.… read more here.
Keywords: protease; kallikrein; second klk; kallikrein related ... See more keywords